Efficacy comparison of multipoint and single point scanning panretinal laser photocoagulation in non-proliferative diabetic retinopathy treatment.

IF 4.2 3区医学 Q1 ENDOCRINOLOGY & METABOLISM World Journal of Diabetes Pub Date : 2024-08-15 DOI:10.4239/wjd.v15.i8.1734

Yang-Zhou Zhang, Hua Gong, Juan Yang, Ji-Pu Bu, Hui-Ling Yang

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Abstract

Background: Non-proliferative diabetic retinopathy (NPDR) poses a significant challenge in diabetes management due to its microvascular changes in the retina. Laser photocoagulation, a conventional therapy, aims to mitigate the risk of progressing to proliferative diabetic retinopathy (PDR).

Aim: To compare the efficacy and safety of multi-spot vs single-spot scanning panretinal laser photocoagulation in NPDR patients.

Methods: Forty-nine NPDR patients (86 eyes) treated between September 2020 and July 2022 were included. They were randomly allocated into single-spot (n = 23, 40 eyes) and multi-spot (n = 26, 46 eyes) groups. Treatment outcomes, including best-corrected visual acuity (BCVA), central macular thickness (CMT), and mean threshold sensitivity, were assessed at predetermined intervals over 12 months. Adverse reactions were also recorded.

Results: Energy levels did not significantly differ between groups (P > 0.05), but the multi-spot group exhibited lower energy density (P < 0.05). BCVA and CMT improvements were noted in the multi-spot group at one-month post-treatment (P < 0.05). Adverse reaction incidence was similar between groups (P > 0.05).

Conclusion: While energy intensity and safety were comparable between modalities, multi-spot scanning demonstrated lower energy density and showed superior short-term improvements in BCVA and CMT for NPDR patients, with reduced laser-induced damage.

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多点扫描和单点扫描全视网膜激光光凝治疗非增殖性糖尿病视网膜病变的疗效比较。

背景：非增殖性糖尿病视网膜病变（NPDR）会引起视网膜微血管病变，是糖尿病治疗中的一大挑战。激光光凝是一种传统疗法，旨在降低进展为增殖性糖尿病视网膜病变（PDR）的风险。目的：比较多点扫描与单点扫描全视网膜激光光凝对 NPDR 患者的疗效和安全性：纳入2020年9月至2022年7月期间接受治疗的49例NPDR患者（86眼）。他们被随机分配到单光斑组（n = 23，40 眼）和多光斑组（n = 26，46 眼）。治疗结果包括最佳矫正视力（BCVA）、黄斑中心厚度（CMT）和平均阈值敏感度，在12个月的预定时间间隔内进行评估。同时还记录了不良反应：各组之间的能量水平无明显差异（P > 0.05），但多点组的能量密度较低（P < 0.05）。治疗后一个月，多点组的 BCVA 和 CMT 均有所改善（P < 0.05）。各组的不良反应发生率相似（P > 0.05）：结论：虽然两种模式的能量强度和安全性相当，但多光斑扫描的能量密度较低，对NPDR患者的BCVA和CMT的短期改善效果较好，激光引起的损伤也较小。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

World Journal of Diabetes ENDOCRINOLOGY & METABOLISM-

自引率

2.40%

发文量

909

期刊介绍： The WJD is a high-quality, peer reviewed, open-access journal. The primary task of WJD is to rapidly publish high-quality original articles, reviews, editorials, and case reports in the field of diabetes. In order to promote productive academic communication, the peer review process for the WJD is transparent; to this end, all published manuscripts are accompanied by the anonymized reviewers’ comments as well as the authors’ responses. The primary aims of the WJD are to improve diagnostic, therapeutic and preventive modalities and the skills of clinicians and to guide clinical practice in diabetes. Scope: Diabetes Complications, Experimental Diabetes Mellitus, Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus, Diabetes, Gestational, Diabetic Angiopathies, Diabetic Cardiomyopathies, Diabetic Coma, Diabetic Ketoacidosis, Diabetic Nephropathies, Diabetic Neuropathies, Donohue Syndrome, Fetal Macrosomia, and Prediabetic State.