The hidden strength of CD8+ T cells in chronic hepatitis B

IF 27.7 1区 医学 Q1 IMMUNOLOGY Nature Immunology Pub Date : 2024-08-28 DOI:10.1038/s41590-024-01939-1
Francesco Andreata, Matteo Iannacone
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Abstract

A distinct subset of attenuated CD8+ T cells that retain crucial cytotoxic functions has been identified in chronic hepatitis B infection and linked to viral control.

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慢性乙型肝炎 CD8+ T 细胞的隐性优势
在慢性乙型肝炎感染中发现了一种独特的减毒 CD8+ T 细胞亚群,它们保留了关键的细胞毒性功能,并与病毒控制有关。
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来源期刊
Nature Immunology
Nature Immunology 医学-免疫学
CiteScore
40.00
自引率
2.30%
发文量
248
审稿时长
4-8 weeks
期刊介绍: Nature Immunology is a monthly journal that publishes the highest quality research in all areas of immunology. The editorial decisions are made by a team of full-time professional editors. The journal prioritizes work that provides translational and/or fundamental insight into the workings of the immune system. It covers a wide range of topics including innate immunity and inflammation, development, immune receptors, signaling and apoptosis, antigen presentation, gene regulation and recombination, cellular and systemic immunity, vaccines, immune tolerance, autoimmunity, tumor immunology, and microbial immunopathology. In addition to publishing significant original research, Nature Immunology also includes comments, News and Views, research highlights, matters arising from readers, and reviews of the literature. The journal serves as a major conduit of top-quality information for the immunology community.
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