Disproportionate Racial Impact against Hepatic Cancer Patients: NIS 2020

Abstract

Introduction

Hepatobiliary cancer is the second leading cause of cancer-related death worldwide. Prior data showed mixed results against racial impact in this population group, with limited specific results regarding clinical outcomes. We aim to utilize a large national database to provide comprehensive data on the clinical outcomes of hepatobiliary cancer about race.

Method

The 2020 National Inpatient Sample was utilized in this study. patients with hepatobiliary cancer were selected by ICD-10 CM code. Inpatient mortality and associated complications, including acute kidney injury (AKI), heart failure, and mechanical ventilation use were analyzed. Logistic regression analysis was used to assess the association between race and complications.

Results

We surveyed 20,670 hospitalizations with hepatobiliary cancer. Caucasians accounted for 60.7%, whereas African Americans accounted for 12%. The mean age was 65.38 years, with 66% being male. African Americans had a significantly higher inpatient mortality rate (aOR 1.61, 95%CI (1.10, 2.35), p <0.005) as well as higher odds of acute kidney injury (aOR 1.22; 95%CI (1.10-1.35), p<0.005) compared to Caucasians. We found increased, but not statistically significant in other clinical outcomes compared to Caucasians.

Conclusion

African Americans are at a higher risk of experiencing worsening clinical outcomes and mortality rates. Future longitudinal studies could shed light on these long-term connections.