Therapeutic Potential of a Biodynamic Supplement on Skin Pressure Ulcers: A Randomized Clinical Study.

IF 3.9 3区 工程技术 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY Biomedicines Pub Date : 2024-08-22 DOI:10.3390/biomedicines12081918
Pasquale Ferorelli, Manfred Doepp, Stefano Lenzi, Roberto Rovelli, Gennaro Gisonna, Giuseppe Maierà, Francesco Antonelli, Massimo Radaelli, Anna Shevchenko, Giordana Feriotto, Carlo Mischiati, Ilaria Borromeo, Simone Beninati
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Abstract

Pressure ulcers (PUs) are a debilitating and often painful condition. They are localized lesions on the skin and/or underlying tissues and are common in the elderly, people with mobility difficulties, diabetics, and vascular disease or malnutrition, as well as in those requiring intensive or palliative care. The prevention and treatment of PUs involve strategies to optimize hydration, circulation, and nutrition. Nutrition plays a key role in pressure ulcer care because wounds require macronutrients and micronutrients to heal. Reports relating to the effectiveness of "Complementary Enzyme Therapy" also in the vulnological field led us to this study, the aim of which was to test the activity of a biodynamic food supplement (Citozym®) rich in carbohydrates, vitamins, and amylase and lactase and characterized by marked antioxidant activity. Citozym® administered topically and/or systemically, and in particular in both administrations, in patients suffering from Pus, has shown a marked reduction in bedsores and, in many cases, complete healing. Furthermore, it was possible to observe a lower incidence of side effects compared to conventional therapies. The results obtained, confirmed by various tests and recognized by the scientific community, allow us to conclude that treatment with Citozym® could represent a new and effective strategy for the treatment of PUs.

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生物动力补充剂对皮肤压疮的治疗潜力:随机临床研究
压疮(PUs)是一种使人衰弱且经常疼痛的疾病。压疮是皮肤和/或下层组织的局部损伤,常见于老年人、行动不便者、糖尿病患者、血管疾病或营养不良患者,以及需要重症监护或姑息治疗的患者。预防和治疗压力性溃疡涉及优化水合、血液循环和营养的策略。营养在压疮护理中起着关键作用,因为伤口愈合需要宏量营养素和微量营养素。有关 "补充酶疗法 "在褥疮治疗领域的有效性的报道促使我们开展了这项研究,其目的是测试一种生物动力食品补充剂(Citozym®)的活性,该补充剂富含碳水化合物、维生素、淀粉酶和乳糖酶,并具有明显的抗氧化活性。对脓疱疮患者局部和/或全身使用 Citozym®,尤其是同时使用这两种药物,褥疮明显减少,很多情况下完全愈合。此外,与传统疗法相比,副作用的发生率也更低。这些结果得到了各种测试的证实和科学界的认可,我们可以得出结论,使用 Citozym® 治疗脓毒症是一种新的有效策略。
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来源期刊
Biomedicines
Biomedicines Biochemistry, Genetics and Molecular Biology-General Biochemistry,Genetics and Molecular Biology
CiteScore
5.20
自引率
8.50%
发文量
2823
审稿时长
8 weeks
期刊介绍: Biomedicines (ISSN 2227-9059; CODEN: BIOMID) is an international, scientific, open access journal on biomedicines published quarterly online by MDPI.
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