{"title":"Pharmacopuncture Improves the Lipid Profile in Patients under Statins: Retrospective Study at a Korean Medicine Clinic.","authors":"Ju-Young Lee, Youngeun Yoo, Sanghun Lee","doi":"","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To assess the efficacy of pharmacopuncture (PA) in improving lipid profiles of patients under statin therapy.</p><p><strong>Design and setting: </strong>Single-center retrospective study.</p><p><strong>Interventions: </strong>Fifty-nine patients who were previously under statins were retrospectively analyzed. We injected 10 cc of PA twice or thrice a week for 12 to 16 weeks at the acupoint (CV5). The PA solution was based on aqueous extracts of various herbs: Taraxaci Herba, Artemisiae Annuae Herba, Elsholtziae Herba, Acanthopanacis Cortex, and Rumecis Radix.</p><p><strong>Main outcome measures: </strong>Lipid profiles, including total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), and triglyceride (TG) levels, were compared before and after PA treatment within patients.</p><p><strong>Results: </strong>The mean age was 59.03 ± 19.82 years, and 50.8% were women (n=30). TC and LDL-C levels decreased from 233.6 ± 54.6 mg/dL to 202.0 ± 26.4 mg/dL (P = 1.27×10-6) and from 175.1 ± 46.2 mg/dL to 133.1 ± 21.6 mg/dL (P = 1.37×10-10), respectively. Interestingly, HDL-C level increased from 30.4 ± 14.6 mg/dL to 43.1 ± 12.1 mg/dL (P = 4.39×10-10), where men demonstrated better improvement than women (P = 1.73×10-3).</p><p><strong>Conclusion: </strong>Our findings highlight the adjuvant effects of PA treatment on the lipid profile in patients under statins and the sex interaction in HDL-C improvement, which provides a clinical foundation for future clinical trials with personalized treatment strategies to establish the clinical benefits of PA treatment with statins.</p>","PeriodicalId":7571,"journal":{"name":"Alternative therapies in health and medicine","volume":null,"pages":null},"PeriodicalIF":1.9000,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Alternative therapies in health and medicine","FirstCategoryId":"3","ListUrlMain":"","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"INTEGRATIVE & COMPLEMENTARY MEDICINE","Score":null,"Total":0}
引用次数: 0
Abstract
Objective: To assess the efficacy of pharmacopuncture (PA) in improving lipid profiles of patients under statin therapy.
Design and setting: Single-center retrospective study.
Interventions: Fifty-nine patients who were previously under statins were retrospectively analyzed. We injected 10 cc of PA twice or thrice a week for 12 to 16 weeks at the acupoint (CV5). The PA solution was based on aqueous extracts of various herbs: Taraxaci Herba, Artemisiae Annuae Herba, Elsholtziae Herba, Acanthopanacis Cortex, and Rumecis Radix.
Main outcome measures: Lipid profiles, including total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), and triglyceride (TG) levels, were compared before and after PA treatment within patients.
Results: The mean age was 59.03 ± 19.82 years, and 50.8% were women (n=30). TC and LDL-C levels decreased from 233.6 ± 54.6 mg/dL to 202.0 ± 26.4 mg/dL (P = 1.27×10-6) and from 175.1 ± 46.2 mg/dL to 133.1 ± 21.6 mg/dL (P = 1.37×10-10), respectively. Interestingly, HDL-C level increased from 30.4 ± 14.6 mg/dL to 43.1 ± 12.1 mg/dL (P = 4.39×10-10), where men demonstrated better improvement than women (P = 1.73×10-3).
Conclusion: Our findings highlight the adjuvant effects of PA treatment on the lipid profile in patients under statins and the sex interaction in HDL-C improvement, which provides a clinical foundation for future clinical trials with personalized treatment strategies to establish the clinical benefits of PA treatment with statins.
期刊介绍:
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