Animal amino acid sensor - A review.

IF 2.4 2区 农林科学 Q1 AGRICULTURE, DAIRY & ANIMAL SCIENCE Animal Bioscience Pub Date : 2025-02-01 Epub Date: 2024-08-26 DOI:10.5713/ab.24.0366
Yongding Ke, Xinyu Peng, Chengchuang Song, Xingtang Fang, Yanhong Wang, Chunlei Zhang
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引用次数: 0

Abstract

Cell growth and metabolism necessitate the involvement of amino acids, which are sensed and integrated by the mammalian target of rapamycin complex 1 (mTORC1). However, the molecular mechanisms underlying amino acid sensing remain poorly understood. Research indicates that amino acids are detected by specific sensors, with the signals being relayed to mTORC1 indirectly. This paper reviews the structures and biological functions of the amino acid sensors identified thus far. Additionally, it evaluates the potential role these sensors play in the developmental changes of the livestock production.

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动物氨基酸传感器
细胞的生长和新陈代谢需要氨基酸的参与,而氨基酸是由哺乳动物雷帕霉素靶标复合体 1(mTORC1)感知和整合的。然而,人们对氨基酸感应的分子机制仍然知之甚少。研究表明,氨基酸是由特定的传感器检测到的,信号间接传递给 mTORC1。本文回顾了迄今发现的氨基酸传感器的结构和生物功能。此外,它还评估了这些传感器在家畜生产的发育变化中所起的潜在作用。
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来源期刊
Animal Bioscience
Animal Bioscience AGRICULTURE, DAIRY & ANIMAL SCIENCE-
CiteScore
5.00
自引率
0.00%
发文量
223
审稿时长
3 months
期刊最新文献
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