Increasing digesta viscosity altered nutrient transporter gene expression and decreased nutrient utilisation in Eimeria-challenged birds.

IF 1.6 3区 农林科学 Q2 AGRICULTURE, DAIRY & ANIMAL SCIENCE British Poultry Science Pub Date : 2024-08-30 DOI:10.1080/00071668.2024.2377276
E O Alagbe, P Jaynes, C S Park, O Adeola
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Abstract

1. Two experiments were conducted, the first was to investigate the effect of increasing digesta viscosity by dietary carboxymethyl cellulose (CMC) on the growth performance and intestinal morphology and characteristics of healthy birds. The second experiment evaluated the impact of increased digesta viscosity in birds during an Eimeria spp. challenge.2. In experiment 1, a corn-soybean meal-based basal diet was supplemented with 0, 10 or 20 g/kg CMC at the expense of cornstarch and offered to seven birds in each of eight replicate cages per diet from d 8 to 22 post hatching.3. Increasing digesta viscosity due to dietary CMC linearly reduced (p < 0.05) body weight (BW) gain and the apparent ileal digestibility of nutrients. The relative lengths of the duodenum, jejunum and ileum linearly increased (p < 0.01) with dietary CMC inclusion.4. In experiment 2, on d 14, 256 broiler chickens were randomly assigned to eight replicate cages in a 2 × 2 factorial arrangement of treatments with two CMC concentrations (0 or 10 g CMC/kg of diet), with or without an Eimeria challenge. On d 15, birds in the challenge groups were orally gavaged with a 1 ml solution containing 25,000, 25,000 or 125,000 oocysts of E. maxima, E. tenella and E. acervulina; or 1% PBS, respectively.5. Increasing digesta viscosity in Eimeria-challenged birds decreased the total tract digestibility of dry matter and gross energy (p < 0.05). The ileal gene expression of glucose transporters was upregulated (p < 0.05) in challenged birds that received the CMC-supplemented diet.6. In summary, increased digesta viscosity induced changes in the expression of nutrient transporter genes and decreased nutrient utilisation in Eimeria-challenged birds.

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增加消化液粘度会改变营养物质转运体基因的表达,并降低感染艾美耳病的鸟类对营养物质的利用率。
1.进行了两项实验,第一项是研究通过日粮羧甲基纤维素(CMC)增加消化液粘度对健康禽类生长性能、肠道形态和特征的影响。2. 在实验 1 中,以玉米-豆粕为基础日粮中添加 0、10 或 20 g/kg CMC,而不添加玉米淀粉,从孵化后第 8 天到第 22 天,每个日粮 8 个重复笼中各饲养 7 只鸟。 3. 日粮 CMC 增加消化液粘度可线性降低(p p Eimeria 挑战)。在孵化后第 15 天,挑战组的鸟分别口服含有 25,000、25,000 或 125,000 个 E. maxima、E. tenella 和 E. acervulina 卵囊的 1 毫升溶液,或 1%的 PBS。 Eimeria 挑战鸟消化液粘度的增加降低了干物质和总能量的总消化率(p p Eimeria 挑战鸟。
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来源期刊
British Poultry Science
British Poultry Science 农林科学-奶制品与动物科学
CiteScore
3.90
自引率
5.00%
发文量
88
审稿时长
4.5 months
期刊介绍: From its first volume in 1960, British Poultry Science has been a leading international journal for poultry scientists and advisers to the poultry industry throughout the world. Over 60% of the independently refereed papers published originate outside the UK. Most typically they report the results of biological studies with an experimental approach which either make an original contribution to fundamental science or are of obvious application to the industry. Subjects which are covered include: anatomy, embryology, biochemistry, biophysics, physiology, reproduction and genetics, behaviour, microbiology, endocrinology, nutrition, environmental science, food science, feeding stuffs and feeding, management and housing welfare, breeding, hatching, poultry meat and egg yields and quality.Papers that adopt a modelling approach or describe the scientific background to new equipment or apparatus directly relevant to the industry are also published. The journal also features rapid publication of Short Communications. Summaries of papers presented at the Spring Meeting of the UK Branch of the WPSA are published in British Poultry Abstracts .
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