Astragali radix (Huangqi): a time-honored nourishing herbal medicine.

IF 5.3 3区医学 Q1 INTEGRATIVE & COMPLEMENTARY MEDICINE Chinese Medicine Pub Date : 2024-08-30 DOI:10.1186/s13020-024-00977-z

Yuyu Zhang, Zhejie Chen, Liping Chen, Qin Dong, Dong-Hua Yang, Qi Zhang, Jing Zeng, Yang Wang, Xiao Liu, Yuan Cui, Minglong Li, Xiao Luo, Chongjian Zhou, Mingzhu Ye, Ling Li, Yuxin He

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Abstract

Astragali radix (AR, namded Huangqi in Chinese) is the dried root of Astragalus membranaceus (Fisch.) Bge. var. mongholicus (Bge.) Hsiao or Astragalus membranaceus (Fisch.) Bge. As a widely used ethnomedicine, the biological activities of AR include immunomodulatory, anti-hyperglycemic, anti-oxidant, anti-aging, anti-inflammatory, anti-viral, anti-tumor, cardioprotective, and anti-diabetic effects, with minimum side effects. Currently, it is known that polysaccharides, saponins, and flavonoids are the indispensable components of AR. In this review, we will elaborate the research advancements of AR on ethnobotany, ethnopharmacological practices, phytochemicals, pharmacological activities, clinical uses, quality control, production developments, and toxicology. The information is expected to assist clinicians and scientists in developing useful therapeutic medicines with minimal systemic side effects.

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黄芪：一种历史悠久的滋补中药。

黄芪（Astragali radix，中文名黄芪）是黄芪科植物黄芪（Astragalus membranaceus (Fisch.) Bge.）或黄芪（Astragalus membranaceus (Fisch.) Bge.）的干燥根。作为一种广泛使用的民族医药，AR 的生物活性包括免疫调节、抗高血糖、抗氧化、抗衰老、抗炎、抗病毒、抗肿瘤、保护心脏和抗糖尿病等作用，且副作用最小。目前已知，多糖、皂苷和黄酮类化合物是 AR 不可或缺的成分。在这篇综述中，我们将阐述 AR 在民族植物学、民族药理学实践、植物化学成分、药理活性、临床用途、质量控制、生产发展和毒理学方面的研究进展。希望这些信息能帮助临床医生和科学家开发出对全身副作用最小的有效治疗药物。

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来源期刊

Chinese Medicine INTEGRATIVE & COMPLEMENTARY MEDICINE-PHARMACOLOGY & PHARMACY

CiteScore

7.90

自引率

4.10%

发文量

133

审稿时长

31 weeks

期刊介绍： Chinese Medicine is an open access, online journal publishing evidence-based, scientifically justified, and ethical research into all aspects of Chinese medicine. Areas of interest include recent advances in herbal medicine, clinical nutrition, clinical diagnosis, acupuncture, pharmaceutics, biomedical sciences, epidemiology, education, informatics, sociology, and psychology that are relevant and significant to Chinese medicine. Examples of research approaches include biomedical experimentation, high-throughput technology, clinical trials, systematic reviews, meta-analysis, sampled surveys, simulation, data curation, statistics, omics, translational medicine, and integrative methodologies. Chinese Medicine is a credible channel to communicate unbiased scientific data, information, and knowledge in Chinese medicine among researchers, clinicians, academics, and students in Chinese medicine and other scientific disciplines of medicine.