Dynamics of hiatal hernia recurrence: how important is a composite crural repair?

IF 2.6 2区 医学 Q1 SURGERY Hernia Pub Date : 2024-10-01 Epub Date: 2024-08-29 DOI:10.1007/s10029-024-03136-3
Francesca M Dimou, Vic Velanovich
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Abstract

Introduction: Hiatal hernia recurrence rates vary widely. The true causes of recurrences are not fully understood but likely multifactorial. Surgical approaches and techniques have evolved over time to try and reduce recurrence rates after hiatal hernia repair. Our objective is to provide a current review on the physiology of hiatal hernias and the importance of a composite crural repair on hiatal hernia recurrence rates; more specifically, for this review, a composite repair is defined as a repair requiring more than primary closure of the crura.

Methods: A recent review of the literature was conducted to identify studies reporting on hiatal hernia pathophysiology, stress, and tension, as well as the role of composite repair.

Results: There is a paucity of studies focusing on the pathophysiology of hiatal hernias and recurrence rates. Articles that report on the pathophysiology of the hiatus were found to have alterations of the extracellular matrix, collagen composition, changes in metalloproteinases (MMPs), and differences in genetic composition. The role of composite repair on reducing recurrence rates is not well studied.

Conclusions: Hiatal hernias remain a complex problem with no ideal surgical technique. It is likely that the pathophysiology of hiatal hernias is multifactorial, and more studies need to be done to better understand the potential underlying mechanisms for hiatal hernias so this may also further identify the ideal surgical repair.

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食管裂孔疝复发的动态变化:复合嵴修补术有多重要?
导言疝气复发率差异很大。复发的真正原因尚不完全清楚,但很可能是多因素造成的。为了降低食管裂孔疝修补术后的复发率,手术方法和技术也在不断发展。我们的目标是对食管裂孔疝的生理学以及复合嵴修补术对食管裂孔疝复发率的重要性进行最新综述;更具体地说,在本综述中,复合修补术被定义为需要对嵴进行一次以上闭合的修补术:方法:对近期文献进行回顾,以确定有关食管裂孔疝病理生理学、压力和张力以及复合修复作用的研究报告:结果:有关食管裂孔疝病理生理学和复发率的研究很少。报道裂孔病理生理学的文章发现,细胞外基质、胶原组成、金属蛋白酶(MMPs)的变化以及基因组成的差异均有改变。复合修复对降低复发率的作用尚未得到充分研究:膈疝仍然是一个复杂的问题,没有理想的手术技术。食管裂孔疝的病理生理学可能是多因素的,需要进行更多的研究以更好地了解食管裂孔疝的潜在潜在机制,从而进一步确定理想的手术修复方法。
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来源期刊
Hernia
Hernia SURGERY-
CiteScore
4.90
自引率
26.10%
发文量
171
审稿时长
4-8 weeks
期刊介绍: Hernia was founded in 1997 by Jean P. Chevrel with the purpose of promoting clinical studies and basic research as they apply to groin hernias and the abdominal wall . Since that time, a true revolution in the field of hernia studies has transformed the field from a ”simple” disease to one that is very specialized. While the majority of surgeries for primary inguinal and abdominal wall hernia are performed in hospitals worldwide, complex situations such as multi recurrences, complications, abdominal wall reconstructions and others are being studied and treated in specialist centers. As a result, major institutions and societies are creating specific parameters and criteria to better address the complexities of hernia surgery. Hernia is a journal written by surgeons who have made abdominal wall surgery their specific field of interest, but we will consider publishing content from any surgeon who wishes to improve the science of this field. The Journal aims to ensure that hernia surgery is safer and easier for surgeons as well as patients, and provides a forum to all surgeons in the exchange of new ideas, results, and important research that is the basis of professional activity.
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