Odontogenic (hematogenic) or sinusopathy (contiguous) brain abscess: Case report.

Claudine Thereza-Bussolaro, Eduarda B Ramos, Anna Ls Yanai, Luiz-Evaristo-Ricci Volpato, Alexandre M Borba
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Abstract

Brain abscess is a rare infectious condition, affecting 0.4 to 0.9 per 100,000 individuals annually, with classic symptoms of fever, headache, and neurological deficits. The origin can be contiguous, hematogenous, due to ruptures of brain barriers, or cryptogenic. Dental infections, such as those related to Gemella morbillorum, are atypical, and when related to odontogenic sinusitis, it is normally unilateral. This report describes a case of peculiar brain abscess, of unconfirmed source, possibly involving sinusitis or periapical odontogenic lesion in an immunocompetent young woman. A 22-year-old patient presented with sinusitis showed by computed tomography, progressing to a brain abscess caused by multidrug-resistant Streptococcus sanguis. Additional cultures revealed Gemella morbillorum in maxillary sinusitis. Treatment involved stereotactic drainage, sinusotomy, and prolonged antibiotic therapy, with recurrence and surgical reintervention, in addition to prophylactic dental extraction and exerese of the brain cyst capsule. Brain abscess represents a significant medical challenge, often posing difficulties in pinpointing its primary infectious source despite the aid of comprehensive laboratory and imaging diagnostics, as evidenced in this case. Timely and targeted intervention in preceding infections assumes paramount importance for effective management, underscoring the indispensable role of a multidisciplinary healthcare team. Active patient engagement and adherence to treatment protocols are imperative to mitigate complications and foster favorable disease progression. Key words:Brain Abscess, Dental Focal Infection, Gemella, Sinusitis, Streptococcus sanguis.

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牙源性(血源性)或窦性(毗连性)脑脓肿:病例报告。
脑脓肿是一种罕见的感染性疾病,每年每 10 万人中有 0.4 至 0.9 人患病,典型症状为发热、头痛和神经功能缺损。脓肿的来源可以是毗连的、血源性的、脑屏障破裂引起的,也可以是隐源性的。牙源性感染,如与摩尔比洛菌(Gemella morbillorum)有关的感染,是一种非典型感染,如果与牙源性鼻窦炎有关,通常是单侧感染。本报告描述了一例特殊的脑脓肿病例,病源未经证实,可能涉及一名免疫功能健全的年轻女性的鼻窦炎或根尖周牙源性病变。一名 22 岁的患者经计算机断层扫描发现患有鼻窦炎,随后发展为由耐多药血清链球菌引起的脑脓肿。另外的培养结果显示,上颌窦炎中存在莫比尔双球菌(Gemella morbillorum)。治疗包括立体定向引流、鼻窦切开术和长期抗生素治疗,除了预防性拔牙和切除脑囊肿囊外,患者还可能复发并再次接受手术治疗。脑脓肿是一项重大的医学挑战,尽管有全面的实验室和影像学诊断辅助,但往往难以确定其主要感染源,本病例就是很好的证明。及时、有针对性地干预之前的感染对于有效治疗至关重要,这也凸显了多学科医疗团队不可或缺的作用。患者的积极参与和对治疗方案的坚持对于减轻并发症和促进疾病进展至关重要。关键词:脑脓肿、牙灶感染、双球菌、鼻窦炎、血链球菌。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
2.70
自引率
0.00%
发文量
118
期刊介绍: Indexed in PUBMED, PubMed Central® (PMC) since 2012 and SCOPUSJournal of Clinical and Experimental Dentistry is an Open Access (free access on-line) - http://www.medicinaoral.com/odo/indice.htm. The aim of the Journal of Clinical and Experimental Dentistry is: - Periodontology - Community and Preventive Dentistry - Esthetic Dentistry - Biomaterials and Bioengineering in Dentistry - Operative Dentistry and Endodontics - Prosthetic Dentistry - Orthodontics - Oral Medicine and Pathology - Odontostomatology for the disabled or special patients - Oral Surgery
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