Effect of working hours on prognosis of acute ischemic stroke patients following alteplase intravenous thrombolysis.

IF 1.4 4区 医学 Q4 MEDICINE, RESEARCH & EXPERIMENTAL Journal of International Medical Research Pub Date : 2024-08-01 DOI:10.1177/03000605241271828
JingDa Wang, XingYang Yi, Qian Mi
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Abstract

Objective: To investigate the effect of hospital working hours on outcomes of patients with acute ischemic stroke 3 months after receiving alteplase intravenous thrombolysis.

Methods: A retrospective analysis was performed on 254 individuals with acute ischemic stroke who received alteplase intravenous thrombolysis between January 2018 and December 2020 either during peak hospital working hours (08:00-17:59; Group A) or off-peak hours (18:00-07:59 the following day; Group B). Patients were also categorized according to which of four peak/off-peak-hour periods they received treatment in: Group 1 (08:00-11:59), Group 2 (12:00-17:59), Group 3 (18:00-21:59), Group 4 (22:00-07:59 the following day). Baseline data and 3-month prognosis were compared across groups. Logistic regression analysis was used to investigate the correlation between hospital working hours and 3-month prognosis.

Results: There were no significant differences in door-to-needle time, onset-to-needle time, 24-hour National Institutes of Health Stroke Scale (NIHSS) score, 7-day NIHSS score or Modified Rankin Score between Groups 1 to 4 or between Groups A and B. Whether treatment was administered during peak or off-peak hours did not significantly affect 3-month prognosis.

Conclusion: At this hospital, differences in the time at which stroke patients were treated were not associated with outcomes.

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阿替普酶静脉溶栓后,工作时间对急性缺血性脑卒中患者预后的影响。
目的研究医院工作时间对急性缺血性脑卒中患者接受阿替普酶静脉溶栓治疗3个月后预后的影响:对2018年1月至2020年12月期间在医院高峰工作时间(08:00-17:59;A组)或非高峰工作时间(18:00-次日07:59;B组)接受阿替普酶静脉溶栓治疗的254名急性缺血性卒中患者进行回顾性分析。患者还根据其接受治疗的四个高峰/非高峰时段进行了分类:第 1 组(08:00-11:59)、第 2 组(12:00-17:59)、第 3 组(18:00-21:59)、第 4 组(22:00-次日 07:59)。比较了各组的基线数据和 3 个月的预后。采用逻辑回归分析研究医院工作时间与 3 个月预后之间的相关性:结果:第1至第4组之间以及A组和B组之间,从门口到进针的时间、从发病到进针的时间、24小时美国国立卫生研究院卒中量表(NIHSS)评分、7天NIHSS评分或改良Rankin评分均无明显差异:在这家医院,卒中患者接受治疗的时间差异与预后无关。
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来源期刊
CiteScore
3.20
自引率
0.00%
发文量
555
审稿时长
1 months
期刊介绍: _Journal of International Medical Research_ is a leading international journal for rapid publication of original medical, pre-clinical and clinical research, reviews, preliminary and pilot studies on a page charge basis. As a service to authors, every article accepted by peer review will be given a full technical edit to make papers as accessible and readable to the international medical community as rapidly as possible. Once the technical edit queries have been answered to the satisfaction of the journal, the paper will be published and made available freely to everyone under a creative commons licence. Symposium proceedings, summaries of presentations or collections of medical, pre-clinical or clinical data on a specific topic are welcome for publication as supplements. Print ISSN: 0300-0605
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