Is the Orthopaedic Trauma Association-Open Fracture Classification (OTA-OFC) Better than the Gustilo-Anderson Classification at Predicting Fracture-Related Infections in the Tibia?

IF 1.6 3区 医学 Q3 ORTHOPEDICS Journal of Orthopaedic Trauma Pub Date : 2024-08-26 DOI:10.1097/BOT.0000000000002907
Philip Khoury, Nina Hazra, Anthony DeMartino, Kevina Birungi-Huff, Gerard P Slobogean, Robert V O'Toole, Nathan N O'Hara
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Abstract

Objectives: To investigate and compare the predictive ability of the Orthopaedic Trauma Association Open Fracture Classification (OTA-OFC) and the Gustilo-Anderson classification systems for fracture-related infections (FRI) in patients with open tibia fractures.

Methods: Design: Retrospective cohort study.

Setting: Academic trauma center.

Patient selection criteria: Patients aged 16 years or older with an operatively treated open tibia fracture (OTA-OTA 41, 42, and 43) between 2010 and 2021.

Outcome measures and comparisons: The primary outcome was FRI. The OTA-OFC and the Gustilo-Anderson classifications were compared in their ability to predict FRI.

Results: 890 patients (mean age, 43 years [range, 17 to 96]; 75% male) with 912 open tibia fractures were included. 142 (16%) had an infection. The OTA-OFC was not significantly better at predicting FRI than the Gustilo-Anderson classification (area under the curve, 0.66 vs. 0.66; P = 0.89). The Gustilo-Anderson classification was a stronger predictor of FRI than any single OTA-OFC domain, explaining 72% of FRI variance. Only the addition of the OTA-OFC wound contamination domain to Gustilo-Anderson significantly increased the variance explained (72% vs. 84%, P = 0.04). Embedded contamination increased the risk of FRI by approximately 10% as the risk of FRI with embedded contamination was 16% for Type I or IIs, 26% for Type IIIAs, 45% for Type IIIBs, and 46% for Type IIICs.

Conclusions: The more complex OTA-OFC system was not better than the Gustilo-Anderson classification system in predicting FRIs in patients with open tibia fractures. Adding embedded wound contamination to the Gustilo-Anderson classification system significantly improved its prognostic ability.

Level of evidence: Prognostic Level II. See Instructions for Authors for a complete description of levels of evidence.

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在预测胫骨骨折相关感染方面,创伤骨科协会-开放性骨折分类 (OTA-OFC) 优于 Gustilo-Anderson 分类吗?
目的研究并比较创伤骨科协会开放性骨折分类(OTA-OFC)和 Gustilo-Anderson 分类系统对开放性胫骨骨折患者骨折相关感染(FRI)的预测能力:设计:回顾性队列研究:地点: 学术创伤中心:患者选择标准:患者选择标准:2010年至2021年期间接受过手术治疗的16岁及以上开放性胫骨骨折患者(OTA-OTA 41、42和43):主要结果为 FRI。比较了 OTA-OFC 和 Gustilo-Anderson 分类预测 FRI 的能力:纳入了 890 名胫骨开放性骨折患者(平均年龄 43 岁[17 至 96 岁];75% 为男性),共 912 例。142例(16%)患者发生了感染。OTA-OFC 对 FRI 的预测效果并没有明显优于 Gustilo-Anderson 分级法(曲线下面积为 0.66 vs. 0.66;P = 0.89)。古斯蒂洛-安德森分类对 FRI 的预测作用强于任何单一的 OTA-OFC 领域,可解释 72% 的 FRI 变异。只有在 Gustilo-Anderson 的基础上增加 OTA-OFC 伤口污染领域,才能显著增加解释的变异(72% vs. 84%,P = 0.04)。嵌入式污染使FRI的风险增加了约10%,因为I型或II型FRI的嵌入式污染风险为16%,IIIA型为26%,IIIB型为45%,IIIC型为46%:在预测开放性胫骨骨折患者的 FRI 方面,更为复杂的 OTA-OFC 系统并不比 Gustilo-Anderson 分类系统更好。在Gustilo-Anderson分类系统中加入嵌入式伤口污染可显著改善其预后能力:预后二级。有关证据级别的完整描述,请参见 "作者须知"。
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来源期刊
Journal of Orthopaedic Trauma
Journal of Orthopaedic Trauma 医学-运动科学
CiteScore
3.90
自引率
8.70%
发文量
396
审稿时长
3-8 weeks
期刊介绍: Journal of Orthopaedic Trauma is devoted exclusively to the diagnosis and management of hard and soft tissue trauma, including injuries to bone, muscle, ligament, and tendons, as well as spinal cord injuries. Under the guidance of a distinguished international board of editors, the journal provides the most current information on diagnostic techniques, new and improved surgical instruments and procedures, surgical implants and prosthetic devices, bioplastics and biometals; and physical therapy and rehabilitation.
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