Radical cholecystectomy without liver resection for peritoneal side early incidental gallbladder cancer.

IF 4.3 3区 医学 Q1 GASTROENTEROLOGY & HEPATOLOGY World Journal of Gastroenterology Pub Date : 2024-08-28 DOI:10.3748/wjg.v30.i32.3739
Gaetano Piccolo, Matteo Barabino, Guglielmo Niccolò Piozzi, Paolo Pietro Bianchi
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Abstract

Gallbladder cancer (GBC) is a rare disease with a poor prognosis. Simple cholecystectomy may be an adequate treatment only for very early disease (Tis, T1a), whereas reoperation is recommended for more advanced disease (T1b and T2). Radical cholecystectomy should have two fundamental objectives: To radically resect the liver parenchyma and to achieve adequate clearance of the lymph nodes. However, recent studies have shown that compared with lymph node dissection alone, liver resection does not improve survival outcomes. The oncological roles of lymphadenectomy and liver resection is distinct. Therefore, for patients with incidental GBC without liver invasion, hepatic resection is not always mandatory.

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针对腹膜侧早期偶发胆囊癌的根治性胆囊切除术,不切除肝脏。
胆囊癌(GBC)是一种罕见的疾病,预后较差。单纯胆囊切除术仅适用于极早期疾病(Tis、T1a),而对于晚期疾病(T1b 和 T2)则建议再次手术。根治性胆囊切除术有两个基本目标:从根本上切除肝实质,并充分清除淋巴结。然而,最近的研究表明,与单纯淋巴结清扫术相比,肝切除术并不能提高生存率。淋巴结清扫术和肝切除术在肿瘤学上的作用截然不同。因此,对于无肝脏侵犯的偶发 GBC 患者,并不总是必须进行肝脏切除。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
World Journal of Gastroenterology
World Journal of Gastroenterology 医学-胃肠肝病学
CiteScore
7.80
自引率
4.70%
发文量
464
审稿时长
2.4 months
期刊介绍: The primary aims of the WJG are to improve diagnostic, therapeutic and preventive modalities and the skills of clinicians and to guide clinical practice in gastroenterology and hepatology.
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