The contributions of fertility during adolescence to disability across the life-course: hypothesized causal pathways, research gaps, and future directions.

IF 1.2 4区 医学 Q2 ANTHROPOLOGY Annals of Human Biology Pub Date : 2024-02-01 Epub Date: 2024-08-29 DOI:10.1080/03014460.2024.2390829
Catherine M Pirkle, Maria P Velez, Tetine L Sentell, Diego G Bassani, Marlos R Domingues, Saionara M A Câmara
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Abstract

Context: Robust associations have been identified between fertility during adolescence and the disablement process, including pathologies, impairments, functional limitations and disability. Limited theoretical or empirical research considers how and why such relationships exist generally or with the individual associated components of disablement.

Objective: To consolidate and critically evaluate literature to describe testable, theory-based hypotheses to guide future research on the mechanisms by which fertility during adolescence contributes to disablement.

Methods: Targeted literature review of research from diverse global settings contextualised in two well-accepted theoretical frameworks in life-course epidemiology: the cumulative risk model and the critical period approach.

Results: Five hypothesised causal pathways linking adolescent fertility to disablement in later life are described: 1) Causal relationship initiated by fertility during adolescence; 2) Common cause(s) for both, such as adverse childhood experiences; 3) Contributing cause(s) to adolescent fertility; 4) Interaction between adolescent fertility and other risk factors; and 5) Critical period effects unique to adolescence. Most research on the topic is on pathologies versus functional limitations and disability.

Conclusion: We highlight promising research avenues to inform future research and interventions on adolescent fertility and the disablement process. This work provides theoretical clarity, identifies research gaps, and offers hypotheses-testing opportunities for future research.

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青春期生育对整个生命过程中残疾的影响:假设的因果途径、研究差距和未来方向。
背景:已确定青春期生育与残疾过程(包括病理、损伤、功能限制和残疾)之间存在密切联系。对这种关系如何以及为何普遍存在或与残疾的各个相关组成部分之间存在这种关系的理论或实证研究十分有限:整合并批判性地评估文献,描述可检验的、基于理论的假设,以指导未来关于青春期生育导致残疾的机制的研究:方法:根据生命历程流行病学中两个广为接受的理论框架:累积风险模型和关键期方法,对全球不同背景下的研究进行有针对性的文献综述:结果:描述了将青春期生育与晚年残疾联系起来的五个假设因果途径:1) 由青春期生育引发的因果关系;2) 两者的共同原因,如不良童年经历;3) 导致青春期生育的原因;4) 青春期生育与其他风险因素之间的相互作用;5) 青春期特有的临界期效应。有关该主题的大多数研究都是关于病理与功能限制和残疾的:我们强调了有前景的研究途径,为今后有关青少年生育和残疾过程的研究和干预措施提供依据。这项工作为未来研究提供了理论清晰度、确定了研究空白并提供了假设检验机会。
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来源期刊
Annals of Human Biology
Annals of Human Biology 生物-公共卫生、环境卫生与职业卫生
CiteScore
3.40
自引率
5.90%
发文量
46
审稿时长
1 months
期刊介绍: Annals of Human Biology is an international, peer-reviewed journal published six times a year in electronic format. The journal reports investigations on the nature, development and causes of human variation, embracing the disciplines of human growth and development, human genetics, physical and biological anthropology, demography, environmental physiology, ecology, epidemiology and global health and ageing research.
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