First clinical experience of total body irradiation using volumetric modulated arc therapy technique in Japan.

Yuki Nozawa, Hideomi Yamashita, Subaru Sawayanagi, Atsuto Katano
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Abstract

Abstract: In recent years, advances in radiotherapy technology have led to the use of high-precision radiotherapy such as volumetric modulated arc therapy (VMAT). Total body irradiation using VMAT technique (VMAT-TBI) was performed for the first time in our hospital. A 56-year-old male patient diagnosed with B-cell acute lymphoblastic leukemia was performed TBI as pretreatment for haploidentical-related peripheral blood stem-cell transplantation. The prescribed dose was 4 Gy for planning target volume in two fractions. The treatment plan was divided into two plans: upper body and lower body with three and two isocenters, respectively. The overall treatment time with VMAT-TBI was approximately 55 min, and it was not significantly longer than that of moving couch techniques. VMAT-TBI is a less burdensome and more accurate treatment for patients, and it may be a useful treatment for TBI.

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日本首次使用容积调制弧治疗技术进行全身照射的临床经验。
摘要:近年来,放疗技术的进步导致了高精度放疗的使用,如体积调制弧治疗(VMAT)。我院首次采用 VMAT 技术(VMAT-TBI)进行全身照射。一名被诊断为B细胞急性淋巴细胞白血病的56岁男性患者接受了全身照射,作为单倍体相关外周血干细胞移植的预处理。计划靶体积的规定剂量为 4 Gy,分两次进行。治疗计划分为两种:上半身和下半身,分别有三个和两个等中心。VMAT-TBI 的总体治疗时间约为 55 分钟,与移动沙发技术相比并无明显延长。VMAT-TBI对患者来说是一种负担更轻、更精确的治疗方法,它可能是治疗创伤性脑损伤的一种有效方法。
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