Post-Transplant Lymphoproliferative Disorder Presenting as a Gastrointestinal Fistulous Tract in a Heart Transplant Recipient: Case Report and Literature Review

IF 0.8 4区 医学 Q4 IMMUNOLOGY Transplantation proceedings Pub Date : 2024-11-01 Epub Date: 2024-08-30 DOI:10.1016/j.transproceed.2024.07.008
Nour Hasan , Ramia Zakhour , Luz Helena Gutierrez Sanchez , Audrey R. Lloyd , Geling Li , Clara L. Ortiz , Cecelia Hutto
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Abstract

We present a challenging case of Epstein-Barr virus–related isolated small bowel post-transplant lymphoproliferative disorder (PTLD) in a pediatric heart transplant recipient presenting as recurrent gastrointestinal (GI) bleeding and subsequently a GI fistulous tract with associated intra-abdominal abscess. Diagnosis was not confirmed until exploratory laparoscopy was performed, with excision of the fistulous tract revealing evidence of PTLD on pathology. Early diagnosis of GI-PTLD remains a challenge, especially if isolated in the small intestine. Diagnosis may rely on positron emission tomography/ computed tomography scan (PET/CT) or invasive intervention to obtain appropriate tissue samples for pathology diagnosis.
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一名心脏移植受者移植后出现胃肠道瘘管的淋巴组织增生性疾病:病例报告和文献综述。
我们介绍了一例与爱泼斯坦-巴氏病毒(Epstein-Barr virus)相关的小肠移植后淋巴组织增生性疾病(PTLD)病例,该病例为小儿心脏移植受者,表现为反复消化道出血,随后出现消化道瘘道并伴有腹腔内脓肿。直到进行了探查性腹腔镜检查后才确诊,病理检查发现瘘管有PTLD的证据。消化道PTLD的早期诊断仍是一项挑战,尤其是在小肠中分离出PTLD时。诊断可能有赖于正电子发射断层扫描/计算机断层扫描(PET/CT)或侵入性干预,以获取适当的组织样本进行病理诊断。
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来源期刊
Transplantation proceedings
Transplantation proceedings 医学-免疫学
CiteScore
1.70
自引率
0.00%
发文量
502
审稿时长
60 days
期刊介绍: Transplantation Proceedings publishes several different categories of manuscripts, all of which undergo extensive peer review by recognized authorities in the field prior to their acceptance for publication. The first type of manuscripts consists of sets of papers providing an in-depth expression of the current state of the art in various rapidly developing components of world transplantation biology and medicine. These manuscripts emanate from congresses of the affiliated transplantation societies, from Symposia sponsored by the Societies, as well as special Conferences and Workshops covering related topics. Transplantation Proceedings also publishes several special sections including publication of Clinical Transplantation Proceedings, being rapid original contributions of preclinical and clinical experiences. These manuscripts undergo review by members of the Editorial Board. Original basic or clinical science articles, clinical trials and case studies can be submitted to the journal?s open access companion title Transplantation Reports.
期刊最新文献
Editorial Board Contents Author Index Simultaneous Heart-Liver Transplant Using Dual-Organ Normothermic Machine Perfusion Following Donation After Circulatory Death: A Case Report A Case of Transplant Kidney Infected Hydronephrosis Complicated by Pyonephrosis 15 Years Post-Transplantation: A Case Report and Literature Review
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