Efectividad de un sistema híbrido de circuito cerrado en pacientes con diabetes tipo 1 durante el ejercicio físico: un estudio descriptivo en la vida real

IF 2.1 4区 医学 Q2 PEDIATRICS Anales de pediatria Pub Date : 2024-09-01 DOI:10.1016/j.anpedi.2024.05.018
Ruben Martin-Payo , Maria del Mar Fernandez-Alvarez , Rebeca García-García , Ángela Pérez-Varela , Shelini Surendran , Isolina Riaño-Galán
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Abstract

Objective

The aim of the study was to describe how physical exercise affects metabolic control, insulin requirements and carbohydrate intake in children who use hybrid closed-loop systems.

Methods

Cross-sectional study design. The sample included 21 children and adolescents diagnosed with type 1 diabetes. During the study, participants were monitored for a period of 7 days to gather comprehensive data on these factors.

Results

Nine participants (42.9%) had switched to exercise mode to raise the target glucose temporarily to 150 mg/dL. The HbA1c values ranged from 5.5% to 7.9% (median, 6.5%; IQR, 0.75). The percentage of time within the target range of 70-180 mg/dL was similar; however, there was an increased duration of hyperglycaemia and more autocorrections on exercise days. The time spent in severe hyperglycaemia (> 250 mg/dL) increased by 2.7% in exercise compared to non-exercise days (P = .02). It is worth noting that hypoglycaemic episodes did not increase during the exercise days compared with non-exercise days.

Conclusion

The hybrid closed-loop system was effective and safe in children and adolescents with type 1 diabetes during the performance of competitive sports in real life.

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混合闭环系统对 1 型糖尿病患者运动时的效果:一项描述性真实生活研究。
研究旨在描述体育锻炼如何影响使用混合闭环系统的儿童的代谢控制、胰岛素需求和碳水化合物摄入量。样本包括 21 名确诊为 1 型糖尿病的儿童和青少年。研究期间,对参与者进行了为期 7 天的监测,以收集有关这些因素的综合数据。结果9 名参与者(42.9%)切换到运动模式,暂时将目标血糖提高到 150 毫克/分升。HbA1c 值介于 5.5% 到 7.9% 之间(中位数为 6.5%;IQR 为 0.75)。在 70-180 毫克/分升目标范围内的时间百分比相似;但是,高血糖持续时间延长,运动日的自动校正次数增多。与非运动日相比,运动日处于严重高血糖状态(250 毫克/分升)的时间增加了 2.7%(P = 0.02)。值得注意的是,与非运动日相比,运动日的低血糖发生率并没有增加。
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来源期刊
Anales de pediatria
Anales de pediatria 医学-小儿科
CiteScore
2.10
自引率
4.80%
发文量
155
审稿时长
44 days
期刊介绍: La Asociación Española de Pediatría tiene como uno de sus objetivos principales la difusión de información científica rigurosa y actualizada sobre las distintas áreas de la pediatría. Anales de Pediatría es el Órgano de Expresión Científica de la Asociación y constituye el vehículo a través del cual se comunican los asociados. Publica trabajos originales sobre investigación clínica en pediatría procedentes de España y países latinoamericanos, así como artículos de revisión elaborados por los mejores profesionales de cada especialidad, las comunicaciones del congreso anual y los libros de actas de la Asociación, y guías de actuación elaboradas por las diferentes Sociedades/Secciones Especializadas integradas en la Asociación Española de Pediatría.
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