"Uterine-type" Extra-uterine High-grade Sarcoma of the Rectovaginal Septum: Case Report and Review of Literature.

IF 1.6 4区 医学 Q3 OBSTETRICS & GYNECOLOGY International Journal of Gynecological Pathology Pub Date : 2024-11-01 Epub Date: 2024-07-29 DOI:10.1097/PGP.0000000000001019
Chirine Khaled, Nicky D'Haene, Jean-Christophe Noël
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Abstract

The rectovaginal septum is an unusual location for neoplastic processes. The majority of these are extensions of tumors of the rectum or vagina. Masses arising primarily from the rectovaginal fascia are rare. Most primary rectovaginal malignant neoplasms are carcinomas that arise in the setting of endometriosis. Sarcomas in this location are exceedingly rare, with only few cases reported in the literature. We report a case of a 44-year-old lady who developed a high-grade sarcoma in the rectovaginal septum in the setting of endometriosis. We also discussed the differential diagnosis of this lady's challenging and unique lesion, which is most probably an extra-uterine "uterine-type" high-grade sarcoma that shows overlapping features of several entities. Moreover, we performed a literature review of sarcomas in this rare location. Given the fact that the rectovaginal septum is a common location for endometriosis, in the case of a rectovaginal neoplasm, a thorough sampling and a careful search for endometriotic lesions are important, as they may be a clue for the diagnosis. Although rare, sarcomas should always be considered in the differential diagnosis of rectovaginal neoplasms.

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直肠阴道隔膜的 "子宫型 "子宫外高级别肉瘤:病例报告和文献综述。
直肠阴道隔是一个不常见的肿瘤位置。其中大多数是直肠或阴道肿瘤的延伸。主要来自直肠阴道筋膜的肿块很少见。大多数原发性直肠阴道恶性肿瘤是在子宫内膜异位症的情况下发生的癌。该部位的肉瘤极为罕见,文献中仅有少数病例报道。我们报告了一例 44 岁女性因子宫内膜异位症在直肠阴道隔发生高级别肉瘤的病例。我们还讨论了对这位女士具有挑战性的独特病变的鉴别诊断,该病变很可能是子宫外 "子宫型 "高级别肉瘤,显示出多个实体的重叠特征。此外,我们还对这一罕见部位的肉瘤进行了文献综述。鉴于直肠阴道隔是子宫内膜异位症的常见部位,在直肠阴道肿瘤的病例中,彻底取样和仔细寻找子宫内膜异位症病灶非常重要,因为它们可能是诊断的线索。肉瘤虽然罕见,但在直肠阴道肿瘤的鉴别诊断中应始终予以考虑。
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来源期刊
CiteScore
3.90
自引率
12.50%
发文量
154
审稿时长
6-12 weeks
期刊介绍: International Journal of Gynecological Pathology is the official journal of the International Society of Gynecological Pathologists (ISGyP), and provides complete and timely coverage of advances in the understanding and management of gynecological disease. Emphasis is placed on investigations in the field of anatomic pathology. Articles devoted to experimental or animal pathology clearly relevant to an understanding of human disease are published, as are pathological and clinicopathological studies and individual case reports that offer new insights.
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