Evaluation of finite element modeling methods for predicting compression screw failure in a custom pelvic implant.

IF 4.3 3区 工程技术 Q1 BIOTECHNOLOGY & APPLIED MICROBIOLOGY Frontiers in Bioengineering and Biotechnology Pub Date : 2024-08-20 eCollection Date: 2024-01-01 DOI:10.3389/fbioe.2024.1420870
Yuhui Zhu, Ata Babazadeh-Naseri, Matthew R W Brake, John E Akin, Geng Li, Valerae O Lewis, Benjamin J Fregly
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Abstract

Introduction: Three-dimensional (3D)-printed custom pelvic implants have become a clinically viable option for patients undergoing pelvic cancer surgery with resection of the hip joint. However, increased clinical utilization has also necessitated improved implant durability, especially with regard to the compression screws used to secure the implant to remaining pelvic bone. This study evaluated six different finite element (FE) screw modeling methods for predicting compression screw pullout and fatigue failure in a custom pelvic implant secured to bone using nine compression screws. Methods: Three modeling methods (tied constraints (TIE), bolt load with constant force (BL-CF), and bolt load with constant length (BL-CL)) generated screw axial forces using functionality built into Abaqus FE software; while the remaining three modeling methods (isotropic pseudo-thermal field (ISO), orthotropic pseudo-thermal field (ORT), and equal-and-opposite force field (FOR)) generated screw axial forces using iterative physics-based relationships that can be implemented in any FE software. The ability of all six modeling methods to match specified screw pretension forces and predict screw pullout and fatigue failure was evaluated using an FE model of a custom pelvic implant with total hip replacement. The applied hip contact forces in the FE model were estimated at two locations in a gait cycle. For each of the nine screws in the custom implant FE model, likelihood of screw pullout failure was predicted using maximum screw axial force, while likelihood of screw fatigue failure was predicted using maximum von Mises stress. Results: The three iterative physics-based modeling methods and the non-iterative Abaqus BL-CL method produced nearly identical predictions for likelihood of screw pullout and fatigue failure, while the other two built-in Abaqus modeling methods yielded vastly different predictions. However, the Abaqus BL-CL method required the least computation time, largely because an iterative process was not needed to induce specified screw pretension forces. Of the three iterative methods, FOR required the fewest iterations and thus the least computation time. Discussion: These findings suggest that the BL-CL screw modeling method is the best option when Abaqus is used for predicting screw pullout and fatigue failure in custom pelvis prostheses, while the iterative physics-based FOR method is the best option if FE software other than Abaqus is used.

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评估用于预测定制骨盆植入物中压缩螺钉失效的有限元建模方法。
简介:三维(3D)打印定制骨盆植入物已成为接受骨盆癌手术并切除髋关节的患者的一种临床可行选择。然而,临床应用的增加也要求提高植入物的耐久性,尤其是用于将植入物固定到剩余骨盆骨的压缩螺钉。本研究评估了六种不同的有限元(FE)螺钉建模方法,用于预测使用九根压缩螺钉将定制骨盆植入物固定到骨上的压缩螺钉拉出和疲劳故障。方法:三种建模方法(绑定约束 (TIE)、恒定力螺栓载荷 (BL-CF) 和恒定长度螺栓载荷 (BL-CL))使用 Abaqus FE 软件内置的功能生成螺钉轴向力;而其余三种建模方法(各向同性伪热场 (ISO)、正交伪热场 (ORT) 和等反力场 (FOR))则使用可在任何 FE 软件中实现的迭代物理关系生成螺钉轴向力。我们使用全髋关节置换定制骨盆植入物的有限元模型评估了所有六种建模方法在匹配指定螺钉预拉力以及预测螺钉拉出和疲劳失效方面的能力。FE 模型中的髋关节接触力是在步态周期中的两个位置估算的。对于定制植入物 FE 模型中的九个螺钉,使用最大螺钉轴向力预测螺钉拉出失效的可能性,而使用最大 von Mises 应力预测螺钉疲劳失效的可能性。结果:三种基于物理学的迭代建模方法和非迭代的 Abaqus BL-CL 方法对螺钉拉出和疲劳失效可能性的预测几乎完全相同,而其他两种内置 Abaqus 建模方法的预测结果却大相径庭。不过,Abaqus BL-CL 方法所需的计算时间最少,这主要是因为不需要迭代过程来产生指定的螺钉预拉力。在三种迭代法中,FOR 所需的迭代次数最少,因此计算时间也最少。讨论:这些研究结果表明,在使用 Abaqus 预测定制骨盆假体的螺钉拉出和疲劳失效时,BL-CL 螺钉建模方法是最佳选择,而在使用 Abaqus 以外的有限元软件时,基于物理学的迭代 FOR 方法是最佳选择。
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来源期刊
Frontiers in Bioengineering and Biotechnology
Frontiers in Bioengineering and Biotechnology Chemical Engineering-Bioengineering
CiteScore
8.30
自引率
5.30%
发文量
2270
审稿时长
12 weeks
期刊介绍: The translation of new discoveries in medicine to clinical routine has never been easy. During the second half of the last century, thanks to the progress in chemistry, biochemistry and pharmacology, we have seen the development and the application of a large number of drugs and devices aimed at the treatment of symptoms, blocking unwanted pathways and, in the case of infectious diseases, fighting the micro-organisms responsible. However, we are facing, today, a dramatic change in the therapeutic approach to pathologies and diseases. Indeed, the challenge of the present and the next decade is to fully restore the physiological status of the diseased organism and to completely regenerate tissue and organs when they are so seriously affected that treatments cannot be limited to the repression of symptoms or to the repair of damage. This is being made possible thanks to the major developments made in basic cell and molecular biology, including stem cell science, growth factor delivery, gene isolation and transfection, the advances in bioengineering and nanotechnology, including development of new biomaterials, biofabrication technologies and use of bioreactors, and the big improvements in diagnostic tools and imaging of cells, tissues and organs. In today`s world, an enhancement of communication between multidisciplinary experts, together with the promotion of joint projects and close collaborations among scientists, engineers, industry people, regulatory agencies and physicians are absolute requirements for the success of any attempt to develop and clinically apply a new biological therapy or an innovative device involving the collective use of biomaterials, cells and/or bioactive molecules. “Frontiers in Bioengineering and Biotechnology” aspires to be a forum for all people involved in the process by bridging the gap too often existing between a discovery in the basic sciences and its clinical application.
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