Heterochromatin: Hiding from the remodeling machines

IF 14.5 1区 生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY Molecular Cell Pub Date : 2024-09-05 DOI:10.1016/j.molcel.2024.08.012
Craig L. Peterson
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引用次数: 0

Abstract

In this issue of Molecular Cell, Sahu et al.1 find that shielding heterochromatin from SWI/SNF chromatin remodelers is essential to maintain and epigenetically propagate pre-existing heterochromatin domains, whereas SWI/SNF action protects facultative heterochromatic regions from premature silencing.

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异染色质:躲避重塑机器的攻击
在本期的《分子细胞》(Molecular Cell)杂志上,Sahu 等人1 发现,保护异染色质不受 SWI/SNF 染色质重塑者的影响,对于维持和表观遗传学上传播先前存在的异染色质结构域至关重要,而 SWI/SNF 的作用则能保护变性异染色质区域免于过早沉默。
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来源期刊
Molecular Cell
Molecular Cell 生物-生化与分子生物学
CiteScore
26.00
自引率
3.80%
发文量
389
审稿时长
1 months
期刊介绍: Molecular Cell is a companion to Cell, the leading journal of biology and the highest-impact journal in the world. Launched in December 1997 and published monthly. Molecular Cell is dedicated to publishing cutting-edge research in molecular biology, focusing on fundamental cellular processes. The journal encompasses a wide range of topics, including DNA replication, recombination, and repair; Chromatin biology and genome organization; Transcription; RNA processing and decay; Non-coding RNA function; Translation; Protein folding, modification, and quality control; Signal transduction pathways; Cell cycle and checkpoints; Cell death; Autophagy; Metabolism.
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