Expanded Combined Loading Injury Criterion for the Human Lumbar Spine Under Dynamic Compression

IF 3 2区 医学 Q3 ENGINEERING, BIOMEDICAL Annals of Biomedical Engineering Pub Date : 2024-09-06 DOI:10.1007/s10439-024-03570-5
Maria Ortiz-Paparoni, Joost Op ‘t Eynde, Christopher Eckersley, Concetta Morino, Mitchell Abrams, Derek Pang, Jason Kait, Frank Pintar, Narayan Yoganandan, Jason Moore, David Barnes, Kathryn Loftis, Cameron R. Bass
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Abstract

Contemporary injury tolerance of the lumbar spine for under-body blast references axial compression and bending moments in a limited range. Since injuries often occur in a wider range of flexion and extension with increased moment contribution, this study expands a previously proposed combined loading injury criterion for the lumbar spine. Fifteen cadaveric lumbar spine failure tests with greater magnitudes of eccentric loading were incorporated into an existing injury criterion to augment its applicability and a combined loading injury risk model was proposed by means of survival analysis. A loglogistic distribution was the most representative of injury risk, resulting in optimized critical values of Fr,crit = 6011 N, and My,crit = 904 Nm for the proposed combined loading metric. The 50% probability of injury resulted in a combined loading metric value of 1, with 0.59 and 1.7 corresponding to 5 and 95% injury risk, respectively. The inclusion of eccentric loaded specimens resulted in an increased contribution of the bending moment relative to the previously investigated flexion/extension range (previous My,crit = 1155 Nm), with the contribution of the resultant sagittal force reduced by nearly 200 N (previous Fr,crit = 5824 N). The new critical values reflect an expanded flexion/extension range of applicability of the previously proposed combined loading injury criterion for the human lumbar spine during dynamic compression.

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人体腰椎在动态挤压下的扩展组合负荷损伤标准
当代腰椎对体下爆炸的损伤耐受性参考了有限范围内的轴向压缩和弯曲力矩。由于损伤通常发生在更大的屈伸范围内,且力矩贡献增大,因此本研究扩展了之前提出的腰椎综合加载损伤标准。在现有的损伤标准中加入了 15 项具有更大偏心载荷的尸体腰椎损伤测试,以增强其适用性,并通过生存分析提出了综合载荷损伤风险模型。对数分布是最能代表损伤风险的分布,从而为所提出的综合加载指标优化了临界值 Fr,crit = 6011 N 和 My,crit = 904 Nm。受伤概率为 50%的组合加载指标值为 1,0.59 和 1.7 分别对应于 5%和 95%的受伤风险。与之前研究的屈伸范围相比,偏心加载试样的加入增加了弯曲力矩的贡献(之前的My,crit = 1155牛米),由此产生的矢状力的贡献减少了近200牛米(之前的Fr,crit = 5824牛米)。新的临界值反映了之前提出的人体腰椎在动态压缩过程中的综合负荷损伤标准的适用范围扩大了。
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来源期刊
Annals of Biomedical Engineering
Annals of Biomedical Engineering 工程技术-工程:生物医学
CiteScore
7.50
自引率
15.80%
发文量
212
审稿时长
3 months
期刊介绍: Annals of Biomedical Engineering is an official journal of the Biomedical Engineering Society, publishing original articles in the major fields of bioengineering and biomedical engineering. The Annals is an interdisciplinary and international journal with the aim to highlight integrated approaches to the solutions of biological and biomedical problems.
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