[SIBO, from myth to reality].

Thomas Escoda, Frédérique Retornaz, Anne Plauzolles, Philippe Halfon
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Abstract

Digestive functional disorders are among the most frequent reasons for medical consultation and a significant source of medical wandering. Therapeutic management of these patients is difficult, particularly due to the absence of specific treatment linked to an incomplete understanding of the pathophysiological mechanisms. In a certain number of these patients, the symptoms are accompanied by a small intestinal bacterial overgrowth (SIBO). This entity, historically identified in specific post-surgical situations, seems finally very common and associated with very diverse pathologies. The diagnosis of SIBO is currently being made more accessible through the development of breathing tests. Therapeutic management, based mainly on antibiotic therapy and diet, remains to date largely empirical because it is based on few studies but the growing interest in SIBO should make it possible to identify effective treatments during robust clinical trials.

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[SIBO,从神话到现实]。
消化功能紊乱是最常见的就诊原因之一,也是医疗纠纷的重要来源。对这些患者的治疗管理十分困难,特别是由于缺乏与病理生理机制不完全了解相关的具体治疗方法。在这些患者中,有一部分人的症状伴随着小肠细菌过度生长(SIBO)。这种病症历来被认为是在特定的手术后情况下出现的,但现在看来却非常常见,而且与多种病症有关。目前,呼吸测试的发展使 SIBO 的诊断更加容易。治疗方法主要以抗生素治疗和饮食为主,由于研究较少,迄今为止基本上仍是经验性的,但随着人们对 SIBO 的兴趣与日俱增,有可能在强有力的临床试验中确定有效的治疗方法。
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