An Aggressively Recurrent Squamous Cell Carcinoma of the Foot.

IF 0.5 4区 医学 Q4 ORTHOPEDICS Journal of the American Podiatric Medical Association Pub Date : 2024-07-01 DOI:10.7547/21-044A
Arthur Tarricone, Allen Gee, Karla De La Mata, Wayne Axman, Cristina Buricea, Michael Trepal, Prakash Krishnan
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Abstract

Squamous cell carcinoma is a malignant tumor that is most commonly found on the head and neck. The current global incidence of squamous cell carcinoma at any site is estimated to be more than 1 million cases per year, with a reported 3-year mortality rate of 30%. Recurrence of squamous cell carcinoma at any site is estimated to be 15% to 50% and has been associated with greater rates of infiltration, perineural invasion, and mortality. Recent studies have shown lower-extremity squamous cell carcinoma to be distinct from squamous cell carcinoma at any site with histologic and clinical differences. Lower-extremity squamous cell carcinoma is suggestively less aggressive and carries less risk of metastasis. However, lower-extremity squamous cell carcinoma prevalence, mortality, and recurrence rates have not been extensively studied. The present report depicts a case of recurrent squamous cell carcinoma originating in 2006 in the dorsal forefoot and provides the clinical management of subsequent recurrence episodes, with excisions from 2015 and 2020.

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侵袭性复发性足部鳞状细胞癌
鳞状细胞癌是一种恶性肿瘤,最常见于头颈部。据估计,目前全球每年任何部位的鳞状细胞癌发病率超过 100 万例,3 年死亡率为 30%。据估计,任何部位的鳞状细胞癌复发率为 15%至 50%,并且与浸润、神经周围侵犯和死亡率较高有关。最近的研究表明,下肢鳞状细胞癌与任何部位的鳞状细胞癌在组织学和临床上都有所不同。下肢鳞状细胞癌的侵袭性较低,转移风险也较小。然而,下肢鳞状细胞癌的发病率、死亡率和复发率尚未得到广泛研究。本报告描述了一例2006年起源于前足背侧的复发性鳞状细胞癌,并提供了2015年和2020年切除的后续复发病例的临床治疗方法。
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来源期刊
CiteScore
1.10
自引率
0.00%
发文量
128
审稿时长
6-12 weeks
期刊介绍: The Journal of the American Podiatric Medical Association, the official journal of the Association, is the oldest and most frequently cited peer-reviewed journal in the profession of foot and ankle medicine. Founded in 1907 and appearing 6 times per year, it publishes research studies, case reports, literature reviews, special communications, clinical correspondence, letters to the editor, book reviews, and various other types of submissions. The Journal is included in major indexing and abstracting services for biomedical literature.
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