João Pedro Tôrres Guimarães , Matheus Bernardes Torres Fogaça , Rodrigo Scaliante Moura , Marcelo Mendonça , Fabricio Rochedo Conceição , João Bosco Lima Gimaque , Talita Heleny Pacheco de Almeida , Cláudia Abrain , Maria Paula Gomes Mourão , Luiz Tadeu Moraes Figueiredo , Mariane Martins Araújo Stefani , Samira Bührer-Sékula
{"title":"Hantavirus: Preliminary assessment of lateral flow immune assay prototypes to detect IgM and IgG antibodies","authors":"João Pedro Tôrres Guimarães , Matheus Bernardes Torres Fogaça , Rodrigo Scaliante Moura , Marcelo Mendonça , Fabricio Rochedo Conceição , João Bosco Lima Gimaque , Talita Heleny Pacheco de Almeida , Cláudia Abrain , Maria Paula Gomes Mourão , Luiz Tadeu Moraes Figueiredo , Mariane Martins Araújo Stefani , Samira Bührer-Sékula","doi":"10.1016/j.diagmicrobio.2024.116521","DOIUrl":null,"url":null,"abstract":"<div><p>Three lateral flow immunoassay prototypes developed to detect IgM, IgG and IgM/IgG antibodies against Hantavirus were evaluated. A total of 163 samples were tested: 10 from Hantavirus patients, 103 from related diseases, and 50 from healthy controls. The prototypes exhibited 100 % sensitivity, 97.5 % to 99.3 % specificity, indicating promising improved diagnosis.</p></div>","PeriodicalId":11329,"journal":{"name":"Diagnostic microbiology and infectious disease","volume":"110 4","pages":"Article 116521"},"PeriodicalIF":2.1000,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Diagnostic microbiology and infectious disease","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S073288932400347X","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}
引用次数: 0
Abstract
Three lateral flow immunoassay prototypes developed to detect IgM, IgG and IgM/IgG antibodies against Hantavirus were evaluated. A total of 163 samples were tested: 10 from Hantavirus patients, 103 from related diseases, and 50 from healthy controls. The prototypes exhibited 100 % sensitivity, 97.5 % to 99.3 % specificity, indicating promising improved diagnosis.
期刊介绍：
Diagnostic Microbiology and Infectious Disease keeps you informed of the latest developments in clinical microbiology and the diagnosis and treatment of infectious diseases. Packed with rigorously peer-reviewed articles and studies in bacteriology, immunology, immunoserology, infectious diseases, mycology, parasitology, and virology, the journal examines new procedures, unusual cases, controversial issues, and important new literature. Diagnostic Microbiology and Infectious Disease distinguished independent editorial board, consisting of experts from many medical specialties, ensures you extensive and authoritative coverage.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
