A detailed methodology for estimating health-related hazards of workplace exposure to indoor formaldehyde vapours

IF 1.6 Q2 MULTIDISCIPLINARY SCIENCES MethodsX Pub Date : 2024-08-28 DOI:10.1016/j.mex.2024.102937
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Abstract

A comprehensive risk assessment method was applied to examine the risks associated with airborne formaldehyde occupational exposure among hospital laboratory staff. The method assessed exposure levels and health impacts by integrating area and personal air sampling, biological monitoring, and self-reported health data. Samples were collected from 74 workplaces across various departments using NIOSH method 3500 and were analyzed via UV-vis spectrophotometry. The data showed significant differences in exposure levels between departments (p≤0.05) and confirmed the efficacy of the method in identifying risk differences. Despite average personal exposure levels being measured lower than occupational limits, individual assessments indicated that some participants surpassed these limits, emphasizing the necessity of personal monitoring for workers with higher risks. The high prevalence of respiratory symptoms, such as cough and wheezing among staff, indicated the need for further investigation and targeted interventions. Although estimated cancer and non-cancer risks were within safe thresholds, the study emphasized the importance of continuous exposure monitoring and the implementation of effective control measures in hospital laboratory departments with formaldehyde emission. This integrated method improved the reliability and generalizability of formaldehyde exposure risk assessments and aided in the development of safe occupational health practices.

  • The method integrated personal and area sampling with advanced calibration for precise occupational exposure evaluation in laboratories.

  • The method used of biomarkers to assess formaldehyde absorption in the body estimating both cancerous and non-cancerous health risks associated with occupational exposure.

  • Addressed traditional method limitations and integrated risk components to improve data reliability for workplace safety and health risk management.

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估算工作场所接触室内甲醛蒸汽对健康危害的详细方法
我们采用了一种综合风险评估方法来研究医院实验室工作人员接触空气中甲醛的职业风险。该方法通过整合区域和个人空气采样、生物监测和自我报告的健康数据来评估接触水平和对健康的影响。采用 NIOSH 3500 方法从不同部门的 74 个工作场所收集样本,并通过紫外可见分光光度法进行分析。数据显示,不同部门之间的暴露水平存在明显差异(p≤0.05),并证实了该方法在识别风险差异方面的有效性。尽管测得的个人平均接触水平低于职业限值,但个人评估结果显示,一些参与者的接触水平超过了这些限值,这强调了对风险较高的工人进行个人监测的必要性。工作人员中出现咳嗽和喘息等呼吸道症状的比例很高,这表明有必要进行进一步调查并采取有针对性的干预措施。虽然估计的癌症和非癌症风险都在安全阈值之内,但这项研究强调了在有甲醛释放的医院实验室部门进行持续暴露监测和实施有效控制措施的重要性。这种综合方法提高了甲醛暴露风险评估的可靠性和可推广性,有助于制定安全的职业健康实践。
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来源期刊
MethodsX
MethodsX Health Professions-Medical Laboratory Technology
CiteScore
3.60
自引率
5.30%
发文量
314
审稿时长
7 weeks
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