Age and racial and ethnic disparities in filled buprenorphine prescriptions post-emergency department visit in Nevada

Olufemi Ajumobi MD, PhD, Sarah Friedman PhD, John Westhoff MD, Michelle Granner PhD, Julie Lucero PhD, Brandon Koch PhD, Karla D. Wagner PhD
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Abstract

Objectives

We described age, gender, race, and ethnicity associations with filling buprenorphine prescriptions post-emergency department (post-ED) visits.

Methods

We analyzed 1.5 years (July 1, 2020–December 31, 2021) of encounter-level Medicaid ED and retail pharmacy claims data obtained from the Nevada Department of Health and Human Services. We studied ED patients with an opioid use disorder (OUD) diagnosis who did not fill a prescription for OUD medications within 6 months before the ED encounter. Using logistic regression, we modeled the associations between the patient's demographic characteristics and the outcome, filling a buprenorphine prescription at a community pharmacy within 14 or 30 days of the ED encounter.

Results

Among 2781 ED visits, representing 2094 patients, the median age was 39 years, 54% were male, 18.5% were Black, 11.7% were Hispanic, and 62.3% were White. Only 4% of the ED visits were followed by a filled buprenorphine prescription. Increasing age (14-day window: adjusted odds ratio (aOR) = 0.965, 95% confidence interval [CI]: 0.948–0.983) and being a Black patient (14-day window: aOR: 0.114, 95% CI 0.036–0.361) were both associated with lower odds of filled buprenorphine prescriptions. These results were similar within 30 days of an ED visit.

Conclusions

Initiation of buprenorphine following an ED visit remains low among Nevadan Medicaid patients and is less likely with increasing age and among Black patients, despite strong evidence supporting its use. Overburdened EDs, lack of attention from managers, and substance use stigma are among possible explanations. When ED clinicians do write buprenorphine prescriptions, peer recovery support could increase the fill rates.

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内华达州急诊室就诊后丁丙诺啡处方的年龄、种族和民族差异
目的 我们描述了年龄、性别、种族和民族与急诊科(ED)就诊后开具丁丙诺啡处方的关系。 方法 我们分析了从内华达州卫生与公众服务部获得的 1.5 年(2020 年 7 月 1 日至 2021 年 12 月 31 日)的医疗补助急诊室和零售药店报销数据。我们对诊断出患有阿片类药物使用障碍 (OUD) 的急诊患者进行了研究,这些患者在急诊就诊前 6 个月内未开具 OUD 药物处方。我们使用逻辑回归法建立了患者人口统计学特征与结果之间的关联模型,即在急诊就诊后 14 天或 30 天内在社区药房开具丁丙诺啡处方。 结果 在代表 2094 名患者的 2781 次急诊就诊中,年龄中位数为 39 岁,54% 为男性,18.5% 为黑人,11.7% 为西班牙裔,62.3% 为白人。只有 4% 的急诊就诊者开具了丁丙诺啡处方。年龄增加(14 天窗口期:调整后的几率比(aOR)= 0.965,95% 置信区间 [CI]:0.948-0.983):0.948-0.983)和黑人患者(14 天窗口期:aOR:0.114,95% 置信区间 [CI]:0.036-0.361)都与开具丁丙诺啡处方的几率较低有关。这些结果在急诊室就诊后 30 天内相似。 结论 在内华达州的医疗补助患者中,急诊就诊后开始使用丁丙诺啡的比例仍然很低,而且随着年龄的增长和黑人患者的增加,使用丁丙诺啡的可能性越来越小,尽管有大量证据支持使用丁丙诺啡。急诊室负担过重、缺乏管理者的关注以及药物使用污名化等都是可能的原因。当急诊室临床医生开出丁丙诺啡处方时,同伴康复支持可以提高处方开出率。
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