Sri Lasya Karjala, Satya Prasad Namala, Phani Krishna Machiraju, Prabu Pandurangan
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引用次数: 0
Abstract
Good's syndrome (GS) is a rare adult-onset thymoma associated with acquired combined B-cell and T-cell immunodeficiency. It has similarities with Common variable immunodeficiency (CVID) in terms of hypogammaglobulinemia and significant risk of invasive bacterial and opportunistic infections. We still have a long way to go in understanding the pathogenesis of Good's syndrome. Here, we describe a case of a middle-aged female with thymoma and recurrent opportunistic infections. Clinico-laboratory evaluation led to a diagnosis of GS and she showed good response to intravenous immunoglobulin. Clinicians should be aware that thymoma can precede the onset of immunodeficiency.
古德综合征（GS）是一种罕见的成人胸腺瘤，与获得性 B 细胞和 T 细胞联合免疫缺陷有关。就低丙种球蛋白血症和感染侵入性细菌和机会性感染的重大风险而言，它与常见可变免疫缺陷症（CVID）有相似之处。我们在了解古德综合征的发病机制方面还有很长的路要走。在此，我们描述了一例患有胸腺瘤和反复机会性感染的中年女性病例。通过临床和实验室评估，她被确诊为古德综合征，并对静脉注射免疫球蛋白表现出良好的反应。临床医生应该意识到，胸腺瘤可能先于免疫缺陷症发病。
期刊介绍：
Oxford Medical Case Reports (OMCR) is an open access, peer-reviewed online journal publishing original and educationally valuable case reports that expand the field of medicine. The journal covers all medical specialities including cardiology, rheumatology, nephrology, oncology, neurology, and reproduction, comprising a comprehensive resource for physicians in all fields and at all stages of training. Oxford Medical Case Reports deposits all articles in PubMed Central (PMC). Physicians and researchers can find your work through PubMed , helping you reach the widest possible audience. The journal is also indexed in the Web of Science Core Collection . Oxford Medical Case Reports publishes case reports under the following categories: Allergy Audiovestibular medicine Cardiology and cardiovascular systems Critical care medicine Dermatology Emergency medicine Endocrinology and metabolism Gastroenterology and hepatology Geriatrics and gerontology Haematology Immunology Infectious diseases and tropical medicine Medical disorders in pregnancy Medical ophthalmology Nephrology Neurology Oncology Paediatrics Pain Palliative medicine Pharmacology and pharmacy Psychiatry Radiology, nuclear medicine, and medical imaging Respiratory disorders Rheumatology Sexual and reproductive health Sports Medicine Substance abuse.
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