Cerebrospinal fluid protein concentration in patients with lumbar spinal stenosis.

Surgical neurology international Pub Date : 2024-08-23 eCollection Date: 2024-01-01 DOI:10.25259/SNI_610_2024

Hitoshi Yamahata, Kosei Ijiri, Fumito Tanabe, Kyoichi Murasumi, Yushi Nagano, Ryutaro Makino, Nayuta Higa, Ryosuke Hanaya

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Abstract

Background: In this study, we examined the impact and degree of lumbar stenosis on cerebrospinal fluid (CSF) protein concentration.

Methods: In this retrospective study, we analyzed protein concentrations in CSF samples of 61 patients with lumbar spinal stenosis (LSS) obtained during pre-operative myelography. Patients were divided into two groups: those showing no block to contrast (Group A) versus those showing medium block to contrast below the lumbar puncture level (Group B).

Results: The CSF protein concentration in Group B (104.3 ± 59 g/dL) patients with medium block was significantly greater than that in Group A (65.1 ± 33 g/dL) patients without medium block.

Conclusion: A higher average CSF protein concentration was seen in Group B patients with significant lumbar stenosis versus Group A patients without significant lumbar stenosis. Theoretically, damage to the cauda equina in patients with LSS may cause these elevated CSF protein levels.

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腰椎管狭窄症患者脑脊液中的蛋白质浓度。

背景：我们研究了腰椎管狭窄对脑脊液（CSF）蛋白浓度的影响和程度：在这项研究中，我们探讨了腰椎管狭窄对脑脊液（CSF）蛋白质浓度的影响和程度：在这项回顾性研究中，我们分析了 61 名腰椎管狭窄（LSS）患者在术前脊髓造影术中获得的 CSF 样本中的蛋白质浓度。患者被分为两组：造影剂无阻滞组（A 组）和腰椎穿刺水平以下造影剂中等阻滞组（B 组）：结果：中度阻滞 B 组患者的 CSF 蛋白浓度（104.3 ± 59 g/dL）明显高于无中度阻滞 A 组患者的 CSF 蛋白浓度（65.1 ± 33 g/dL）：结论：有明显腰椎管狭窄的 B 组患者的 CSF 蛋白平均浓度高于无明显腰椎管狭窄的 A 组患者。从理论上讲，腰椎管狭窄症患者的马尾受损可能会导致 CSF 蛋白水平升高。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Surgical neurology international

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