Discontinuous hyperpolarization schemes in liquid-state overhauser dynamic nuclear polarization experiments

Alex van der Ham
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Abstract

Liquid-state Overhauser Dynamic Nuclear Polarization (ODNP) is an emerging technique, aimed at shortening NMR experiment times. It achieves this by increasing the otherwise poor nuclear polarization at room temperature, by polarization transfer from excited electron spins. The present work explores two ideas, aimed at achieving the optimal signal-to-noise per time unit for a given system, and quantitation of spectra showing a large disparity in ODNP enhancements at high magnetic fields (≥ 9.4 T). Both of these ideas are predicated on, perhaps counterintuitively, not allowing full dynamic nuclear polarization to build up, either by rapid rf pulsing, or gating of the microwave irradiation.

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液态超豪斯动态核极化实验中的非连续超极化方案
液态奥弗豪斯动态核极化(ODNP)是一项新兴技术,旨在缩短核磁共振实验时间。它通过激发电子自旋的极化转移,提高室温下原本较差的核极化,从而实现这一目标。本研究探讨了两个想法,旨在实现特定系统单位时间内的最佳信噪比,以及对高磁场(≥ 9.4 T)下 ODNP 增强差异较大的光谱进行量化。这两个想法的前提都是,通过快速的射频脉冲或微波辐照的门控,不允许建立完全的动态核极化,这可能与直觉相反。
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