Infectious intracranial aneurysm associated with Lactococcus garvieae: A case report and literature review

Chung-Ho Lee , Peter Yat-Ming Woo , Calvin Ka-Lam Leung , Ronald Li , Jenny Kwan-Tsz Chan , Kwan-Shun Ng , Cindy Wing-Sze Tse
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Abstract

Lactococcus garvieae is a known fish pathogen associated with numerous aquacultural outbreaks. In humans, L. garvieae primarily causes infective endocarditis, but infections involving other organs have also been reported. We report the first case of ruptured infectious intracranial aneurysm associated with L. garvieae bacteraemia without concomitant infective endocarditis. The diagnosis of a left distal posterior cerebral artery mycotic aneurysm was based on a computed tomography angiogram, catheter angiogram and histopathological examination of the resected aneurysm. Here, we review the literature on human L. garvieae infections and describe the clinical characteristics, risk factors, management and outcomes of the cases identified to date.

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与加维氏乳球菌相关的感染性颅内动脉瘤:病例报告和文献综述
加维氏乳球菌(Lactococcus garvieae)是一种已知的鱼类病原体,曾多次在水产养殖业中爆发。在人类中,L. garvieae 主要引起感染性心内膜炎,但也有涉及其他器官感染的报道。我们报告了首例与加维氏梭菌菌血症相关的感染性颅内动脉瘤破裂病例,该病例未同时伴有感染性心内膜炎。根据计算机断层扫描血管造影、导管血管造影和切除动脉瘤的组织病理学检查,诊断为左侧大脑后动脉远端霉菌性动脉瘤。在此,我们回顾了有关人类L. garvieae感染的文献,并描述了迄今发现的病例的临床特征、风险因素、管理和结果。
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