A hand-in-hand phenomenon in older adults: Increased risk of frailty in geriatric outpatients associated with handgrip strength asymmetry and weakness

IF 6.6 2区 医学 Q1 NUTRITION & DIETETICS Clinical nutrition Pub Date : 2024-09-06 DOI:10.1016/j.clnu.2024.09.010
Merve Güner , Serdar Ceylan , Arzu Okyar Baş , Meltem Koca , Yelda Öztürk , Burcu Balam Doğu , Meltem Gülhan Hali̇l , Mustafa Cankurtaran , Cafer Balci
{"title":"A hand-in-hand phenomenon in older adults: Increased risk of frailty in geriatric outpatients associated with handgrip strength asymmetry and weakness","authors":"Merve Güner ,&nbsp;Serdar Ceylan ,&nbsp;Arzu Okyar Baş ,&nbsp;Meltem Koca ,&nbsp;Yelda Öztürk ,&nbsp;Burcu Balam Doğu ,&nbsp;Meltem Gülhan Hali̇l ,&nbsp;Mustafa Cankurtaran ,&nbsp;Cafer Balci","doi":"10.1016/j.clnu.2024.09.010","DOIUrl":null,"url":null,"abstract":"<div><h3>Objectives</h3><p>Handgrip strength (HGS) is accepted as a predictor of overall health status and a biomarker of aging, besides negative health outcomes and mortality. While differences in HGS between the dominant and non-dominant hands are expected, substantial discrepancies may signal impaired muscle function. This study aims to investigate whether handgrip asymmetry can serve as a reliable indicator of frailty in a diverse population of older adults.</p></div><div><h3>Design</h3><p>Cross-sectional study.</p></div><div><h3>Setting and participants</h3><p>A total of 512 patients aged 65 years and older who were admitted to the geriatric medicine outpatient clinic of a university hospital were enrolled in the study.</p></div><div><h3>Methods</h3><p>The Clinical Frailty Scale (CFS) was used to assess the overall level of frailty of the study population. The highest recorded HGS values from the non-dominant and dominant hand were used to calculate the HGS ratio. Those with a HGS ratio of dominant and non-dominant hand &lt;0.90 or &gt;1.10 were defined as HGS asymmetry.</p></div><div><h3>Results</h3><p>Of the whole study group, 61.1% was female and the mean age was 73.2 ± 6.1 years. The ratio of the participants living with frailty was 57.6% (n = 219). The number of patients with HGS asymmetry was 264 (51.6%), and 48.4% (n = 248) of the study population had symmetric HGS. The normal and symmetric HGS was found in 40.2% of the non-frail group, whereas it was 23.7% in patients living with frailty. Furthermore, the ratio of low and asymmetric HGS was 16.3% in the non-frail group, and 35.0% in the patients living with frailty (p &lt; 0.001). The presence of asymmetric and low HGS increased the risk of frailty three times independently of other confounding factors (OR:3.08; 95% CI:1.48–6.43; p = 0.003).</p></div><div><h3>Conclusions and implications</h3><p>Identifying HGS asymmetry along with low HGS as potential indicators of frailty may provide clinicians with a clear and quantifiable criterion for assessing older patients.</p></div>","PeriodicalId":10517,"journal":{"name":"Clinical nutrition","volume":"43 10","pages":"Pages 2381-2387"},"PeriodicalIF":6.6000,"publicationDate":"2024-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical nutrition","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0261561424003297","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"NUTRITION & DIETETICS","Score":null,"Total":0}
引用次数: 0

Abstract

Objectives

Handgrip strength (HGS) is accepted as a predictor of overall health status and a biomarker of aging, besides negative health outcomes and mortality. While differences in HGS between the dominant and non-dominant hands are expected, substantial discrepancies may signal impaired muscle function. This study aims to investigate whether handgrip asymmetry can serve as a reliable indicator of frailty in a diverse population of older adults.

Design

Cross-sectional study.

Setting and participants

A total of 512 patients aged 65 years and older who were admitted to the geriatric medicine outpatient clinic of a university hospital were enrolled in the study.

Methods

The Clinical Frailty Scale (CFS) was used to assess the overall level of frailty of the study population. The highest recorded HGS values from the non-dominant and dominant hand were used to calculate the HGS ratio. Those with a HGS ratio of dominant and non-dominant hand <0.90 or >1.10 were defined as HGS asymmetry.

Results

Of the whole study group, 61.1% was female and the mean age was 73.2 ± 6.1 years. The ratio of the participants living with frailty was 57.6% (n = 219). The number of patients with HGS asymmetry was 264 (51.6%), and 48.4% (n = 248) of the study population had symmetric HGS. The normal and symmetric HGS was found in 40.2% of the non-frail group, whereas it was 23.7% in patients living with frailty. Furthermore, the ratio of low and asymmetric HGS was 16.3% in the non-frail group, and 35.0% in the patients living with frailty (p < 0.001). The presence of asymmetric and low HGS increased the risk of frailty three times independently of other confounding factors (OR:3.08; 95% CI:1.48–6.43; p = 0.003).

Conclusions and implications

Identifying HGS asymmetry along with low HGS as potential indicators of frailty may provide clinicians with a clear and quantifiable criterion for assessing older patients.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
老年人的牵手现象:老年门诊病人体弱的风险增加与手部握力不对称和无力有关
目的手握力(HGS)被认为是预测总体健康状况的指标,也是衰老的生物标志物,此外还能预测负面健康状况和死亡率。虽然惯用手和非惯用手之间的握力差异是意料之中的,但巨大的差异可能预示着肌肉功能受损。本研究旨在探讨手握不对称是否可作为不同老年人群虚弱程度的可靠指标。方法采用临床虚弱量表(CFS)评估研究人群的整体虚弱程度。用非惯用手和惯用手的最高 HGS 值计算 HGS 比率。结果 在整个研究组中,61.1% 为女性,平均年龄为 73.2 ± 6.1 岁。年老体弱者占 57.6%(219 人)。HGS不对称的患者人数为264人(51.6%),48.4%(n = 248)的研究人群HGS对称。在非体弱组中,40.2%的患者HGS正常且对称,而在体弱患者中,这一比例为23.7%。此外,在非体弱组中,HGS 偏低和不对称的比例为 16.3%,而在体弱患者中,这一比例为 35.0%(p <0.001)。结论和意义将 HGS 不对称和低 HGS 识别为虚弱的潜在指标,可为临床医生评估老年患者提供一个明确且可量化的标准。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Clinical nutrition
Clinical nutrition 医学-营养学
CiteScore
14.10
自引率
6.30%
发文量
356
审稿时长
28 days
期刊介绍: Clinical Nutrition, the official journal of ESPEN, The European Society for Clinical Nutrition and Metabolism, is an international journal providing essential scientific information on nutritional and metabolic care and the relationship between nutrition and disease both in the setting of basic science and clinical practice. Published bi-monthly, each issue combines original articles and reviews providing an invaluable reference for any specialist concerned with these fields.
期刊最新文献
Reply - Letter to the editor entitled "Letter to editor - Dietary and lifestyle inflammation scores in relation to colorectal cancer recurrence and all-cause mortality: A longitudinal analysis". Nourishing sustainability: Clinical nutrition's impact on climate change. Letter to Editor–Dietary and lifestyle inflammation scores in relation to colorectal cancer recurrence and all-cause mortality: A longitudinal analysis Letter to the Editor–“Dietary and lifestyle inflammation scores in relation to colorectal cancer recurrence and all-cause mortality: A longitudinal analysis” Implementing the Global Leadership Initiative on Malnutrition (GLIM) criteria in Crohn's disease: Prevalence of malnutrition and association with clinical outcomes
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1