Coordination Compounds of 3d Metals with 2,4-Dimethylpyrazolo[1,5-а]benzimidazole: Magnetic and Biological Properties

IF 1.1 3区化学 Q4 CHEMISTRY, INORGANIC & NUCLEAR Russian Journal of Coordination Chemistry Pub Date : 2024-08-21 DOI:10.1134/S1070328424600621

O. G. Shakirova, T. A. Kuz’menko, N. V. Kurat’eva, L. S. Klyushova, A. N. Lavrov, L. G. Lavrenova

{"title":"Coordination Compounds of 3d Metals with 2,4-Dimethylpyrazolo[1,5-а]benzimidazole: Magnetic and Biological Properties","authors":"O. G. Shakirova, T. A. Kuz’menko, N. V. Kurat’eva, L. S. Klyushova, A. N. Lavrov, L. G. Lavrenova","doi":"10.1134/S1070328424600621","DOIUrl":null,"url":null,"abstract":"New coordination compounds of copper(I), copper(II), cobalt(II), and nickel(II) with 2,4-dimethylpyrazolo[1,5-а]benzimidazole (L) were synthesized and studied. The complexes [CuLCl] (I), [CuLBr] (II), [CuL2Cl2] (III), [CuL2(NO3)2]·H2O (IV), [CoL2Cl2]·0.5H2O (V), [CoL2(NO3)2]·0.5H2O (VI), and [NiL2(NO3)2]·0.5H2O (VII) were studied by IR spectroscopy and powder and single crystal X-ray diffraction (CCDC nos. 2321779 ([CuL2Cl2]), 2321780 ([CoL2(NO3)2])). The results indicate that the coordination polyhedron in 2,4-dimethylpyrazolo[1,5-а]benzimidazole complexes is formed by the nitrogen atoms of the monodentate ligand and the coordinated anion. The cytotoxic and cytostatic properties of L and complexes I–III were studied in relation to the HepG2 hepatocellular carcinoma cells.","PeriodicalId":759,"journal":{"name":"Russian Journal of Coordination Chemistry","volume":null,"pages":null},"PeriodicalIF":1.1000,"publicationDate":"2024-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Russian Journal of Coordination Chemistry","FirstCategoryId":"92","ListUrlMain":"https://link.springer.com/article/10.1134/S1070328424600621","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CHEMISTRY, INORGANIC & NUCLEAR","Score":null,"Total":0}

引用次数: 0

Abstract

New coordination compounds of copper(I), copper(II), cobalt(II), and nickel(II) with 2,4-dimethylpyrazolo[1,5-а]benzimidazole (L) were synthesized and studied. The complexes [CuLCl] (I), [CuLBr] (II), [CuL₂Cl₂] (III), [CuL₂(NO₃)₂]·H₂O (IV), [CoL₂Cl₂]·0.5H₂O (V), [CoL₂(NO₃)₂]·0.5H₂O (VI), and [NiL₂(NO₃)₂]·0.5H₂O (VII) were studied by IR spectroscopy and powder and single crystal X-ray diffraction (CCDC nos. 2321779 ([CuL₂Cl₂]), 2321780 ([CoL₂(NO₃)₂])). The results indicate that the coordination polyhedron in 2,4-dimethylpyrazolo[1,5-а]benzimidazole complexes is formed by the nitrogen atoms of the monodentate ligand and the coordinated anion. The cytotoxic and cytostatic properties of L and complexes I–III were studied in relation to the HepG2 hepatocellular carcinoma cells.

Abstract Image

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

3d 金属与 2,4-二甲基吡唑并[1,5-а]苯并咪唑的配位化合物：磁性和生物特性

摘要合成并研究了铜(I)、铜(II)、钴(II)和镍(II)与 2,4-二甲基吡唑并[1,5-а]苯并咪唑(L)的新型配位化合物。复合物 [CuLCl] (I)、[CuLBr] (II)、[CuL2Cl2] (III)、[CuL2(NO3)2]-H2O (IV)、[CoL2Cl2]-0.5H2O (V)、[CoL2(NO3)2]-0.5H2O (VI) 和 [NiL2(NO3)2]-0.5H2O（VII）进行了红外光谱、粉末和单晶 X 射线衍射（CCDC 编号：2321779（[CuL2Cl2]）、2321780（[CoL2(NO3)2]））研究。结果表明，2,4-二甲基吡唑并[1,5-а]苯并咪唑配合物中的配位多面体是由单齿配体的氮原子和配位阴离子形成的。研究了 L 和配合物 I-III 对 HepG2 肝癌细胞的细胞毒性和细胞抑制特性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Russian Journal of Coordination Chemistry 化学-无机化学与核化学

CiteScore

2.40

自引率

15.80%

发文量

审稿时长

7.2 months

期刊介绍： Russian Journal of Coordination Chemistry is a journal that publishes reviews, original papers, and short communications on all aspects of theoretical and experimental coordination chemistry. Modern coordination chemistry is an interdisciplinary science that makes a bridge between inorganic, organic, physical, analytical, and biological chemistry.