Association and risk of metabolic syndrome and kidney stone disease: outcomes from a systematic review and meta-analysis.

IF 2.1 3区医学 Q2 UROLOGY & NEPHROLOGY Current Opinion in Urology Pub Date : 2024-09-10 DOI:10.1097/mou.0000000000001227

Sohani N Dassanayake,Tanguy Lafont,Bhaskar K Somani

{"title":"Association and risk of metabolic syndrome and kidney stone disease: outcomes from a systematic review and meta-analysis.","authors":"Sohani N Dassanayake,Tanguy Lafont,Bhaskar K Somani","doi":"10.1097/mou.0000000000001227","DOIUrl":null,"url":null,"abstract":"PURPOSE OF REVIEW\r\nMetabolic syndrome (MetS) has emerged as a potential contributor to the development of kidney stone disease (KSD). This study aims to conduct a systematic review of the literature, and meta-analysis of the association between MetS and KSD.\r\n\r\nRECENT FINDINGS\r\nSystematic review revealed Fifteen articles (433 201 patients) were eligible for analysis. Meta-analysis of 11 studies identified a statistically significant association between MetS and KSD with unadjusted odds ratio of 2.02 [95% confidence interval (CI) 1.96-2.08, P < 0.001], and pooled adjusted odds ratio of 1.22 [95% CI 1.09-1.37, P < 0.001]. Of the different MetS traits, hypertension and impaired glucose tolerance were the most significantly associated with KSD.\r\n\r\nSUMMARY\r\nThis study confirms a significant association between MetS and KSD. Despite variations in MetS definitions across different studies analysed, consistent associations were observed across studies. This may have clinical implications in that guidelines do not currently recommend routine MetS screening in KSD patients.","PeriodicalId":11093,"journal":{"name":"Current Opinion in Urology","volume":"24 1","pages":""},"PeriodicalIF":2.1000,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Opinion in Urology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/mou.0000000000001227","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"UROLOGY & NEPHROLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

PURPOSE OF REVIEW Metabolic syndrome (MetS) has emerged as a potential contributor to the development of kidney stone disease (KSD). This study aims to conduct a systematic review of the literature, and meta-analysis of the association between MetS and KSD. RECENT FINDINGS Systematic review revealed Fifteen articles (433 201 patients) were eligible for analysis. Meta-analysis of 11 studies identified a statistically significant association between MetS and KSD with unadjusted odds ratio of 2.02 [95% confidence interval (CI) 1.96-2.08, P < 0.001], and pooled adjusted odds ratio of 1.22 [95% CI 1.09-1.37, P < 0.001]. Of the different MetS traits, hypertension and impaired glucose tolerance were the most significantly associated with KSD. SUMMARY This study confirms a significant association between MetS and KSD. Despite variations in MetS definitions across different studies analysed, consistent associations were observed across studies. This may have clinical implications in that guidelines do not currently recommend routine MetS screening in KSD patients.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

代谢综合征与肾结石疾病的关系和风险：系统回顾和荟萃分析的结果。

综述目的代谢综合征（Metabolic Syndrome，MTS）已成为肾结石病（KSD）发病的潜在诱因。本研究旨在对相关文献进行系统综述，并对代谢综合征与肾结石病之间的关系进行荟萃分析。对 11 项研究进行的元分析发现，MetS 与 KSD 之间存在显著的统计学关联，未调整的几率比为 2.02 [95% 置信区间 (CI) 1.96-2.08，P < 0.001]，汇总调整后的几率比为 1.22 [95% CI 1.09-1.37，P < 0.001]。在不同的 MetS 特征中，高血压和糖耐量受损与 KSD 的关系最为显著。尽管所分析的不同研究对 MetS 的定义存在差异，但在不同研究中观察到了一致的关联。这可能会对临床产生影响，因为目前的指南并不建议对 KSD 患者进行常规 MetS 筛查。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Current Opinion in Urology 医学-泌尿学与肾脏学

CiteScore

5.00

自引率

4.00%

发文量

140

审稿时长

6-12 weeks

期刊介绍： Current Opinion in Urology delivers a broad-based perspective on the most recent and most exciting developments in urology from across the world. Published bimonthly and featuring ten key topics – including focuses on prostate cancer, bladder cancer and minimally invasive urology – the journal’s renowned team of guest editors ensure a balanced, expert assessment of the recently published literature in each respective field with insightful editorials and on-the-mark invited reviews.