Intermittent Fasting and Probiotics: Synergistic Modulation of Gut Health for Therapeutic Advantages

IF 4.4 2区 生物学 Q1 BIOTECHNOLOGY & APPLIED MICROBIOLOGY Probiotics and Antimicrobial Proteins Pub Date : 2024-09-11 DOI:10.1007/s12602-024-10358-5
Amna Shehbaz, Muhammad Afzaal, Noor Akram, Farhan Saeed, Warda Khan, Faiyaz Ahmed, Aftab Ahmed, Aasma Asghar, Zargham Faisal
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Abstract

Intermittent fasting (IF) is an increasingly popular dietary approach involving alternating fasting and eating periods. This review aims to summarize the growing body of literature demonstrating that IF is a potential nutritional practice that involves alternating periods of fasting and eating and the numerous benefits of IF, especially in the modulation of healthy gut microbiota. The positive impact of intermittent fasting on gut microbiota not only promotes gastrointestinal health but also has far-reaching effects on critical systems throughout the body. Additionally, the evidence presented in this review highlights the significant preventive and therapeutic effects of intermittent fasting on a wide range of disorders. This includes reducing the risk of diabetes, and neurological disorders, alleviating obesity, and enhancing the functioning of the liver, ultimately contributing to the maintenance of metabolic equilibrium. Perhaps most notably, these effects play a substantial role in preventing diabetes, a global health concern of increasing significance. This comprehensive investigation delves into the scientific foundations of intermittent fasting’s impact on gut microbiota and its implications for averting chronic diseases, providing valuable insights for future research and therapeutic applications.

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间歇性禁食和益生菌:协同调节肠道健康,发挥治疗优势
间歇性禁食(IF)是一种越来越流行的饮食方法,它涉及禁食和进食的交替时期。本综述旨在总结越来越多的文献,这些文献表明,间歇性禁食是一种潜在的营养方法,包括禁食和进食交替进行,以及间歇性禁食的诸多益处,尤其是在调节健康肠道微生物群方面。间歇性禁食对肠道微生物群的积极影响不仅能促进肠胃健康,还对全身的关键系统产生深远影响。此外,本综述提供的证据还强调了间歇性禁食对多种疾病的显著预防和治疗效果。这包括降低罹患糖尿病和神经系统疾病的风险、减轻肥胖症、增强肝脏功能,最终有助于维持新陈代谢平衡。也许最值得注意的是,这些作用在预防糖尿病方面发挥了重要作用,而糖尿病是一个日益重要的全球健康问题。这项全面的研究深入探讨了间歇性禁食对肠道微生物群影响的科学基础及其对避免慢性疾病的意义,为未来的研究和治疗应用提供了宝贵的见解。
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来源期刊
Probiotics and Antimicrobial Proteins
Probiotics and Antimicrobial Proteins BIOTECHNOLOGY & APPLIED MICROBIOLOGYMICROB-MICROBIOLOGY
CiteScore
11.30
自引率
6.10%
发文量
140
期刊介绍: Probiotics and Antimicrobial Proteins publishes reviews, original articles, letters and short notes and technical/methodological communications aimed at advancing fundamental knowledge and exploration of the applications of probiotics, natural antimicrobial proteins and their derivatives in biomedical, agricultural, veterinary, food, and cosmetic products. The Journal welcomes fundamental research articles and reports on applications of these microorganisms and substances, and encourages structural studies and studies that correlate the structure and functional properties of antimicrobial proteins.
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