Developing a National Study That Integrates the Geriatric Assessment into the Care of Older Patients with Myeloid Malignancies

IF 4.7 2区 医学 Q1 ONCOLOGY Current Oncology Reports Pub Date : 2024-09-11 DOI:10.1007/s11912-024-01600-y
Vijaya Raj Bhatt
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Abstract

Purpose of Review

To highlight the priorities in geriatric assessment research in myeloid malignancies and discuss design considerations necessary to ensure research is patient-centric, generalizeable, and high quality.

Recent Findings

Older adults with myeloid malignancies including those who are perceived to have excellent performance status have multiple functional impairments. These impairments are associated with early mortality. Older adults have different functional trajectories through the course of treatment; this will be further investigated in our ongoing multicenter study. In a single-center study, we have demonstrated the use of geriatric assessment to guide treatment is feasible.

Summary

Key priorities include designing a multicenter validation study to confirm the role of geriatric assessment in determining treatment tolerance and survival. Such a study should include core geriatric assessment measures and should enroll diverse patient population across various practices. Conducting such a study is necessary to advance patient care and trial design, and to open venues to conduct studies to confirm the role of geriatric assessment in treatment selection.

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开展一项全国性研究,将老年评估纳入老年髓系恶性肿瘤患者的护理中
综述目的强调髓系恶性肿瘤老年评估研究的优先事项,并讨论确保研究以患者为中心、可推广和高质量所需的设计考虑因素。这些损伤与早期死亡率有关。老年人在治疗过程中会出现不同的功能障碍;我们正在进行的多中心研究将对此进行进一步调查。总结重点包括设计一项多中心验证研究,以确认老年评估在确定治疗耐受性和存活率方面的作用。这项研究应包括核心老年病学评估措施,并应招募不同诊疗机构的不同患者人群。有必要开展这样的研究,以促进患者护理和试验设计,并为开展研究以确认老年评估在治疗选择中的作用开辟道路。
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来源期刊
CiteScore
8.50
自引率
0.00%
发文量
187
审稿时长
6-12 weeks
期刊介绍: This journal aims to review the most important, recently published clinical findings in the field of oncology. By providing clear, insightful, balanced contributions by international experts, the journal intends to serve all those involved in the care of those affected by cancer. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas, such as cancer prevention, leukemia, melanoma, neuro-oncology, and palliative medicine. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research. Commentaries from well-known figures in the field are also provided.
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