A flexible electrochemical sensor based on Fe-doped polydopamine derived carbon for simultaneous detection of dopamine and uric acid

IF 2.7 3区 化学 Q2 CHEMISTRY, ANALYTICAL Analytical Methods Pub Date : 2024-09-03 DOI:10.1039/d4ay00980k
Xinyu Wang, Wenbin Wang, Meng Gao, Min Fu, Linzheng Ma, Wei Chen
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Abstract

A free-standing electrode was developed based on carbon cloth-supported Fe doped polydopamine derived carbon (Fe/PDA-C/CC) for detection of dopamine (DA) and uric acid (UA) simultaneously. First, dopamine was self-polymerized on the surface of carbon cloth to obtain the polydopamine coatings. Then, Fe3+ was introduced by the formation of coordinate bond with the hydroxyl functional group in the polydopamine layer. After calcination, a flexible and free-standing electrode was obtained. The sensing performance and mechanism of the Fe/PDA-C/CC sensor was investigated and discussed in detail. The experiment results demonstrated that the Fe/PDA-C/CC could simultaneous detection of DA and UA with a wide detection range of 0.5-300 μM and 0.5-400 μM, with low detection limits of 0.041 μM and 0.012 μM, respectively. Meanwhile, the Fe/PDA-C/CC possessed excellent anti-interference, repeatability, stability, as well as accuracy in real samples. Overall, this study provided a facile and effect approach for simultaneous detection of UA and DA.
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基于掺杂铁的多巴胺衍生碳的柔性电化学传感器,用于同时检测多巴胺和尿酸
基于碳布支撑的掺杂铁的聚多巴胺衍生碳(Fe/PDA-C/CC)开发了一种独立电极,用于同时检测多巴胺(DA)和尿酸(UA)。首先,在碳布表面自聚多巴胺,得到多巴胺涂层。然后,通过与多巴胺涂层中的羟基官能团形成配位键引入 Fe3+。经过煅烧后,就得到了柔性独立电极。实验详细研究并讨论了 Fe/PDA-C/CC 传感器的传感性能和机理。实验结果表明,Fe/PDA-C/CC 可同时检测 DA 和 UA,检测范围分别为 0.5-300 μM 和 0.5-400 μM,检出限分别为 0.041 μM 和 0.012 μM。同时,Fe/PDA-C/CC 在实际样品中具有良好的抗干扰性、重复性、稳定性和准确性。总之,该研究为同时检测 UA 和 DA 提供了一种简便有效的方法。
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来源期刊
Analytical Methods
Analytical Methods CHEMISTRY, ANALYTICAL-FOOD SCIENCE & TECHNOLOGY
CiteScore
5.10
自引率
3.20%
发文量
569
审稿时长
1.8 months
期刊介绍: Early applied demonstrations of new analytical methods with clear societal impact
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