Mapping Worldwide Antibiotic Use in Dental Practices: A Scoping Review

Fatemeh Soleymani, Carlos Pérez-Albacete Martínez, Mehrdad Makiabadi, José Eduardo Maté Sánchez de Val
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Abstract

Antibiotic resistance is a critical issue today, necessitating the monitoring of antibiotic usage across various sectors. To determine the defined daily doses (DDDs) of antibiotics prescribed by dentists globally, a comprehensive search was conducted in PubMed, ProQuest, ScienceDirect, Web of Science, Scopus, and EBSCOhost, resulting in the inclusion of 15 documents in this scoping review. The DDD per 1000 inhabitants per day (DID) for oral antibiotics prescribed by dentists for the studied countries was generally below 2.11, with the exception of South Korea, which had a DDD per 1000 patients per day (DPD) of less than 6.97. Most countries, except Croatia and Belgium, demonstrated a decreasing trend in DID before the COVID-19 pandemic, but restrictions during the pandemic led to an increase in these numbers. Penicillin-derived antibiotics were the most commonly prescribed antibiotic among dentists in most countries. This study highlights significant gaps and missing data regarding antibiotics prescribed by dentists worldwide. However, it also indicates that the publication of guidelines, education, and evaluation of antibiotic use can lead to more controlled and appropriate prescriptions among dental professionals.
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绘制全球牙科诊所抗生素使用图:范围审查
抗生素耐药性是当今的一个重要问题,因此有必要对各行各业的抗生素使用情况进行监控。为了确定全球牙医处方抗生素的规定日剂量 (DDD),我们在 PubMed、ProQuest、ScienceDirect、Web of Science、Scopus 和 EBSCOhost 上进行了全面搜索,最终将 15 篇文献纳入了此次范围界定综述。在所研究的国家中,牙医每天为每 1000 名居民开具的口服抗生素处方量(DDD)普遍低于 2.11,但韩国除外,该国每天为每 1000 名患者开具的口服抗生素处方量(DDD)低于 6.97。除克罗地亚和比利时外,大多数国家的 DID 在 COVID-19 大流行前呈下降趋势,但在大流行期间的限制措施导致了这些数字的增加。青霉素类抗生素是大多数国家牙医最常用的处方抗生素。这项研究凸显了全球牙医处方抗生素方面的巨大差距和数据缺失。不过,它也表明,发布指南、开展教育和评估抗生素的使用,可以使牙科专业人员开出更有控制和更适当的处方。
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