{"title":"Incompetent neck valves threaten the aging brain","authors":"Monica M. Santisteban, Costantino Iadecola","doi":"10.1038/s43587-024-00707-y","DOIUrl":null,"url":null,"abstract":"Cervical lymphatic vessels drain cerebrospinal fluid from the brain. A recent study reveals an aging-related disruption in the pumping action of lymphatic vessels that hampers lymph flow, which may prevent efficient brain clearance of potentially toxic proteins linked to neurodegenerative disease.","PeriodicalId":94150,"journal":{"name":"Nature aging","volume":null,"pages":null},"PeriodicalIF":17.0000,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature aging","FirstCategoryId":"1085","ListUrlMain":"https://www.nature.com/articles/s43587-024-00707-y","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CELL BIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Cervical lymphatic vessels drain cerebrospinal fluid from the brain. A recent study reveals an aging-related disruption in the pumping action of lymphatic vessels that hampers lymph flow, which may prevent efficient brain clearance of potentially toxic proteins linked to neurodegenerative disease.
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