Gut microbiome compositional and functional features associate with Alzheimer’s disease pathology

Jea Woo Kang, Lora A. Khatib, Margo B. Heston, Amanda H. Dilmore, Jennifer S. Labus, Yuetiva Deming, Leyla Schimmel, Colette Blach, Daniel McDonald, Antonio Gonzalez, MacKenzie Bryant, Karenina Sanders, Lara Schwartz, Tyler K. Ulland, Sterling C. Johnson, Sanjay Asthana, Cynthia M. Carlsson, Nathaniel A. Chin, Kaj Blennow, Henrik Zetterberg, Federico E. Rey, Alzheimer Gut Microbiome Project Consortium, Rima Kaddurah-Daouk, Rob Knight, Barbara B. Bendlin
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Abstract

BACKGROUND The gut microbiome is a potentially modifiable factor in Alzheimer’s disease (AD); however, understanding of its composition and function regarding AD pathology is limited.
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肠道微生物组的组成和功能特征与阿尔茨海默病的病理相关联
背景 肠道微生物组是阿尔茨海默病(AD)的一个潜在可调节因素;然而,人们对肠道微生物组在阿尔茨海默病病理方面的组成和功能的了解还很有限。
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