Karissa DiMarzio, Darlynn M. Rojo-Wissar, Evelyn Hernandez Valencia, Mikayla Ver Pault, Shane Denherder, Adamari Lopez, Jena Lerch, Georgette Metrailer, Sarah M. Merrill, April Highlander, Justin Parent
{"title":"Childhood Adversity and Adolescent Epigenetic Age Acceleration: The Role of Adolescent Sleep Health","authors":"Karissa DiMarzio, Darlynn M. Rojo-Wissar, Evelyn Hernandez Valencia, Mikayla Ver Pault, Shane Denherder, Adamari Lopez, Jena Lerch, Georgette Metrailer, Sarah M. Merrill, April Highlander, Justin Parent","doi":"10.1101/2024.09.02.24312939","DOIUrl":null,"url":null,"abstract":"<strong>Study Objectives</strong> We investigated how a dimension of early life adversity (ELA) capturing threat in the home relates to later epigenetic age acceleration in adolescence through sleep (duration, efficiency, and timing), to empirically test theoretical models suggesting the importance of sleep as a key mechanism linking ELA with poor health outcomes, and to expand the limited literature on sleep and epigenetic aging among youth.","PeriodicalId":501388,"journal":{"name":"medRxiv - Psychiatry and Clinical Psychology","volume":"192 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"medRxiv - Psychiatry and Clinical Psychology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1101/2024.09.02.24312939","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Study Objectives We investigated how a dimension of early life adversity (ELA) capturing threat in the home relates to later epigenetic age acceleration in adolescence through sleep (duration, efficiency, and timing), to empirically test theoretical models suggesting the importance of sleep as a key mechanism linking ELA with poor health outcomes, and to expand the limited literature on sleep and epigenetic aging among youth.