Photocatalytic Destruction of Ceftriaxone in Aqueous Solutions

IF 0.7 4区化学 Q4 CHEMISTRY, PHYSICAL Russian Journal of Physical Chemistry A Pub Date : 2024-09-11 DOI:10.1134/s0036024424701395

M. R. Sizykh, A. A. Batoeva, K. D. Alekseev

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Abstract

The kinetic tendencies in the destruction of cephalosporin antibiotics (ceftriaxone (CEF)) in photoinitiated oxidative systems were studied using a xenon lamp as a source of quasisolar radiation (UV–Vis). It was established that the oxidative systems under study can be arranged in the following series according to the efficiency and rate of antibiotic destruction: {UV–Vis/Fe²⁺/S₂O\(_{8}^{{2 - }}\)} > {Fe²⁺/S₂O\(_{8}^{{2 - }}\)} \( \gg \) {UV–Vis/S₂O\(_{8}^{{2 - }}\)} > {UV–Vis}. The optimum conditions for the oxidative destruction of CEF in the {UV–Vis/Fe²⁺/S₂O\(_{8}^{{2 - }}\)} system are reached at [S₂O\(_{8}^{{2 - }}\)] : [CEF] = 30 : 1 and [S₂O\(_{8}^{{2 - }}\)] : [Fe²⁺] = 1 : 0.1. As the temperature increases to 40°C, the initial CEF oxidation rate and efficiency increase. The apparent activation energy of the CEF oxidation in the {UV–Vis/Fe²⁺/S₂O\(_{8}^{{2 - }}\)} system was 45 kJ mol^–1, which is comparable to the values obtained for cephalosporin antibiotics. It was proved, using inhibitors of radical reactions, that the oxidative destruction of CEF in combined {UV–Vis/Fe²⁺/S₂O\(_{8}^{{2 - }}\)} proceeds by a multiradical mechanism involving reactive oxygen species (ROS): hydroxyl radicals and sulfate and superoxide radical anions. The obtained tendencies are in good agreement with the results of open-air studies with natural solar radiation; in the {Solar/Fe²⁺/S₂O\(_{8}^{{2 - }}\)} system, the oxidation of CEF is significantly intensified due to combined activation of persulfate by the iron ions, the UV-C (<300 nm) component of natural solar radiation, and the thermal exposure. The results indicate that using the combined {Solar/Fe²⁺/S₂O\(_{8}^{{2 - }}\)} oxidation system is promising for the destruction of antibiotics in order to reduce their release into the environment.

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光催化破坏水溶液中的头孢曲松

摘要以氙灯作为准太阳辐射源（紫外可见光），研究了头孢菌素类抗生素（头孢曲松（CEF））在光引发氧化体系中的破坏动力学趋势。结果表明，根据抗生素破坏的效率和速度，所研究的氧化体系可分为以下系列：{UV-Vis/Fe2+/S2O\(_{8}^{2 - }}} > {Fe2+/S2O\(_{8}^{2 - }}\)} \( \gg \) {UV-Vis/S2O\(_{8}^{2 - }}} > {UV-Vis}。在{UV-Vis/Fe2+/S2O/(_{8}^{2 - }}\)} 系统中，[S2O/(_{8}^{2 - }}\)] : [CEF] = 30 : 1 和 [S2O\(_{8}^{2 - }}\)] : [Fe2+] = 1 : 0.1 是 CEF 氧化破坏的最佳条件。当温度升高到 40°C 时，CEF 的初始氧化速率和效率都会增加。在{UV-Vis/Fe2+/S2O/(_{8}^{{2 - }}\)}体系中，CEF 氧化的表观活化能为 45 kJ mol-1，与头孢菌素类抗生素得到的数值相当。利用自由基反应抑制剂证明，在组合{UV-Vis/Fe2+/S2O/(_{8}^{{2 - }}\)} 中，CEF 的氧化破坏是通过多自由基机制进行的，其中涉及活性氧（ROS）：羟自由基、硫酸根和超氧自由基阴离子。所获得的趋势与利用天然太阳辐射进行露天研究的结果非常一致；在{Solar/Fe2+/S2O\(_{8}^{2 - }}\)}系统中，由于铁离子、天然太阳辐射中的紫外线-C（<300 nm）成分和热暴露共同激活了过硫酸盐，CEF 的氧化作用显著增强。结果表明，使用{Solar/Fe2+/S2O/(_{8}^{2 - }}\)} 组合氧化系统有望破坏抗生素，从而减少其在环境中的释放。

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来源期刊

Russian Journal of Physical Chemistry A 化学-物理化学

CiteScore

1.20

自引率

14.30%

发文量

376

审稿时长

5.1 months

期刊介绍： Russian Journal of Physical Chemistry A. Focus on Chemistry (Zhurnal Fizicheskoi Khimii), founded in 1930, offers a comprehensive review of theoretical and experimental research from the Russian Academy of Sciences, leading research and academic centers from Russia and from all over the world. Articles are devoted to chemical thermodynamics and thermochemistry, biophysical chemistry, photochemistry and magnetochemistry, materials structure, quantum chemistry, physical chemistry of nanomaterials and solutions, surface phenomena and adsorption, and methods and techniques of physicochemical studies.