E. Yu. Tyunina, G. N. Tarasova, I. N. Mezhevoi, D. R. Stavnova
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引用次数: 0
Abstract
Densimetry is used to study the interaction between L-histidine (His) and nicotinic (NA), isonicotinic (INA), and picolinic acids (PA) in an aqueous buffer solution in the 288.15–313.15 K range of temperatures. Data on density are used to determine the apparent molar volumes and limiting apparent molar volumes of pyridine monocarboxylic acid (PyCOOH) isomers at infinite dilution, along with their temperature derivatives in a buffer solution containing the amino acid. Unlike the linear concentration dependences of the apparent molar volume of PyCOOH isomers in a buffer solution, the analogous dependences of ternary systems (PyCOOH–His–buffer) are nonlinear, indicating the formation of a molecular complex between the solutes. Limiting apparent molar expansibilities and their temperature derivatives are determined. Their values suggest that the ordering of the solvent grows in the series of isomers PA → NA → INA upon adding the amino acid to a buffer solution of PyCOOH. It is shown that the limiting apparent molar volumes of transferring PyCOOH from a buffer to a His-containing buffer solution have positive values and grow in the studied range of temperatures. The discussion of the results is based on the dominant types of molecular interactions between the solute and solvent using the Gurney model.
摘要密度测量法用于研究 L-组氨酸（His）与烟酸（NA）、异烟酸（INA）和皮考林酸（PA）在水缓冲溶液中的相互作用，温度范围为 288.15-313.15 K。密度数据用于确定无限稀释时吡啶单羧酸（PyCOOH）异构体的表观摩尔体积和极限表观摩尔体积，以及它们在含有氨基酸的缓冲溶液中的温度衍生物。与 PyCOOH 异构体在缓冲溶液中的表观摩尔体积的线性浓度依赖关系不同，三元系统（PyCOOH-His-缓冲溶液）的类似依赖关系是非线性的，表明溶质之间形成了分子复合物。我们测定了极限表观摩尔膨胀率及其温度导数。它们的值表明，在 PyCOOH 缓冲溶液中加入氨基酸后，溶剂的有序性在 PA → NA → INA 的异构体系列中增长。研究表明，将 PyCOOH 从缓冲溶液转移到含 His 的缓冲溶液的极限表观摩尔体积为正值，并在研究的温度范围内增长。对结果的讨论基于使用 Gurney 模型的溶质和溶剂之间的主要分子相互作用类型。
期刊介绍：
Russian Journal of Physical Chemistry A. Focus on Chemistry (Zhurnal Fizicheskoi Khimii), founded in 1930, offers a comprehensive review of theoretical and experimental research from the Russian Academy of Sciences, leading research and academic centers from Russia and from all over the world.
Articles are devoted to chemical thermodynamics and thermochemistry, biophysical chemistry, photochemistry and magnetochemistry, materials structure, quantum chemistry, physical chemistry of nanomaterials and solutions, surface phenomena and adsorption, and methods and techniques of physicochemical studies.
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