Repetitive Transcranial Magnetic Stimulation Modulates Brain Connectivity in Children with Self-limited Epilepsy with Centrotemporal Spikes

Xiwei She, Wendy Qi, Kerry C. Nix, Miguel Menchaca, Christopher C. Cline, Wei Wu, Zihuai He, Fiona M. Baumer
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Abstract

Objective Interictal epileptiform discharges (IEDs) alter brain connectivity in children with epilepsy; this connectivity change may be a mechanism by which epilepsy induces cognitive deficits. Here, we test whether repetitive transcranial magnetic stimulation (rTMS), a non-invasive neuromodulation technique, modulates connectivity and reduces IEDs in children with epilepsy.
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重复经颅磁刺激可调节自限性癫痫患儿大脑的连接性,并伴有颞中棘波
目的发作间期癫痫样放电(IED)会改变癫痫患儿的大脑连通性;这种连通性的改变可能是癫痫诱发认知障碍的一种机制。在此,我们测试了重复经颅磁刺激(rTMS)这种非侵入性神经调节技术是否能调节癫痫患儿的连接性并减少 IED。
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