A DOUBLE-BLIND, PLACEBO-CONTROLLED, RANDOMIZED, MULTI-CENTRE, PHASE III STUDY OF MLC901 (NEUROAID II™) FOR THE TREATMENT OF COGNITIVE IMPAIRMENT AFTER MILD TRAUMATIC BRAIN INJURY

Pavel I. Pilipenko, Anna A. Ivanova, Yulia V. Kotsiubinskaya, Vera N. Grigoryeva, Alexey Y. Khrulev, Anatoly V. Skorokhodov, Maxim M. Gavrik, Nona N. Mkrtchan, Marek Majdan, Peter Valkovic, Daria Babarova, Suzanne Barker-Collo, Kelly Jones, Valery L. Feigin
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Abstract

Introduction About half of the world population will suffer from a traumatic brain injury (TBI) during their lifetime, of which about 90% of cases are mild TBI. About 15-40% of adults with TBI experience persistent cognitive deficits, and there is a lack of proven-effective treatment to facilitate cognitive recovery after mild TBI.
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MLC901(neuroaid II™)治疗轻度脑外伤后认知障碍的双盲、安慰剂对照、随机、多中心、III 期研究
导言 世界上大约有一半的人在一生中会遭受创伤性脑损伤(TBI),其中约 90% 的病例属于轻度 TBI。约 15-40% 的成人创伤性脑损伤患者会出现持续的认知障碍,而目前尚缺乏行之有效的治疗方法来促进轻度创伤性脑损伤后的认知恢复。
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