S Renjini, Akhilash Mohanan Pillai, Pinky Abraham, P A Pavitha
{"title":"Electrochemical synthesis of graphene oxide/palladium composite for the detection of norepinephrine in the presence of ascorbic acid and uric acid","authors":"S Renjini, Akhilash Mohanan Pillai, Pinky Abraham, P A Pavitha","doi":"10.1007/s11581-024-05758-0","DOIUrl":null,"url":null,"abstract":"<p>In the present study, an electrochemically reduced graphene oxide/palladium-modified glassy carbon electrode (ERGO-Pd/GCE) was successfully synthesized by single-step electrodeposition and employed for the determination of norepinephrine (NE). The modified GCE exhibited enhanced sensitivity towards the simultaneous and selective determination of NE, uric acid (UA), and ascorbic acid (AA). The electrochemical performances were evaluated using cyclic voltammetry (CV), differential pulse voltammetry (DPV), and chronoamperometry (CA). This sensor was also effective for the simultaneous detection of epinephrine (EP), UA, and AA. Moreover, the sensor showed outstanding long-term stability, reproducibility, and repeatability. Thus, the electrochemical sensor developed in this study was successfully employed for real samples, such as human blood serum.</p>","PeriodicalId":599,"journal":{"name":"Ionics","volume":null,"pages":null},"PeriodicalIF":2.4000,"publicationDate":"2024-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Ionics","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1007/s11581-024-05758-0","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, PHYSICAL","Score":null,"Total":0}
引用次数: 0
Abstract
In the present study, an electrochemically reduced graphene oxide/palladium-modified glassy carbon electrode (ERGO-Pd/GCE) was successfully synthesized by single-step electrodeposition and employed for the determination of norepinephrine (NE). The modified GCE exhibited enhanced sensitivity towards the simultaneous and selective determination of NE, uric acid (UA), and ascorbic acid (AA). The electrochemical performances were evaluated using cyclic voltammetry (CV), differential pulse voltammetry (DPV), and chronoamperometry (CA). This sensor was also effective for the simultaneous detection of epinephrine (EP), UA, and AA. Moreover, the sensor showed outstanding long-term stability, reproducibility, and repeatability. Thus, the electrochemical sensor developed in this study was successfully employed for real samples, such as human blood serum.
期刊介绍：
Ionics is publishing original results in the fields of science and technology of ionic motion. This includes theoretical, experimental and practical work on electrolytes, electrode, ionic/electronic interfaces, ionic transport aspects of corrosion, galvanic cells, e.g. for thermodynamic and kinetic studies, batteries, fuel cells, sensors and electrochromics. Fast solid ionic conductors are presently providing new opportunities in view of several advantages, in addition to conventional liquid electrolytes.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
