Analysis of a mathematical model for malaria using data-driven approach

Adithya Rajnarayanan, Manoj Kumar
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Abstract

Malaria is one of the deadliest diseases in the world, every year millions of people become victims of this disease and many even lose their lives. Medical professionals and the government could take accurate measures to protect the people only when the disease dynamics are understood clearly. In this work, we propose a compartmental model to study the dynamics of malaria. We consider the transmission rate dependent on temperature and altitude. We performed the steady state analysis on the proposed model and checked the stability of the disease-free and endemic steady state. An artificial neural network (ANN) is applied to the formulated model to predict the trajectory of all five compartments following the mathematical analysis. Three different neural network architectures namely Artificial neural network (ANN), convolution neural network (CNN), and Recurrent neural network (RNN) are used to estimate these parameters from the trajectory of the data. To understand the severity of a disease, it is essential to calculate the risk associated with the disease. In this work, the risk is calculated using dynamic mode decomposition(DMD) from the trajectory of the infected people.
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利用数据驱动方法分析疟疾数学模型
疟疾是世界上最致命的疾病之一,每年都有数百万人成为这种疾病的受害者,许多人甚至失去了生命。医学专家和政府只有清楚地了解这种疾病的动态,才能采取准确的措施保护人民。在这项工作中,我们提出了一个研究疟疾动态的分室模型。我们考虑了传播率与温度和海拔的关系。我们对提出的模型进行了稳态分析,并检验了无病稳态和流行稳态的稳定性。在数学分析之后,我们将人工神经网络(ANN)应用于所建立的模型,以预测所有五个分区的轨迹。三种不同的神经网络架构,即人工神经网络(ANN)、卷积神经网络(CNN)和循环神经网络(RNN)被用来从数据轨迹中估计这些参数。为了了解疾病的严重程度,必须计算与疾病相关的风险。在这项工作中,使用动态模式分解(DMD)从感染者的轨迹中计算风险。
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