V. B. Markeev, E. V. Blynskaya, S. V. Tishkov, K. V. Alekseev, V. K. Alekseev
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引用次数: 0
Abstract
The Heckel and Kawakita equations are the most common mathematical models used in modern studies of the pressing process to evaluate the mechanical properties of tablets. However, these classical models do not take into account the whole spectrum of processes occurring during interparticle interaction, which necessitates the development of new approaches to modeling the tableting process. For this reason, a rather large number of direct- pressing models have now been developed. The choice of the optimal equation for each specific case has become a nontrivial problem. Currently used mathematical descriptions of the direct-pressing process were analyzed in the present study.
期刊介绍：
Pharmaceutical Chemistry Journal is a monthly publication devoted to scientific and technical research on the creation of new drugs and the improvement of manufacturing technology of drugs and intermediates. International contributors cover the entire spectrum of new drug research, including:
methods of synthesis;
results of pharmacological, toxicological, and biochemical studies;
investigation of structure - activity relationships in prediction of new compounds;
methods and technical facilities used; and
problems associated with the development of ecologically safe and economically feasible methods of industrial production.
In addition, analytical reviews of the international literature in the field provide coverage of the most recent developments around the world.
Pharmaceutical Chemistry Journal is a translation of the Russian journal Khimiko-Farmatsevticheskii Zhurnal. The Russian Volume Year is published in English from April.
All articles are peer-reviewed.
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