Design of Synthetic Strategies towards Sulfur Containing Scaffolds

Synthesis Pub Date : 2024-08-28 DOI:10.1055/s-0043-1775393
Sambasivarao Kotha, Priti Khedkar
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Abstract

The utilization of sulfur heterocycles in organic synthesis has attracted significant attention due to their wide-ranging applications. This review showcases the syntheses of diverse sulfur heterocycles embedded with amino acid derivatives, polycycles, spirocycles, cyclophanes, and other complex scaffolds. The reported methods extend beyond compound synthesis and highlight the use of different sulfur reagents for constructing sulfur heterocycles. This Review also discusses the utility of a variety of sulfur-containing starting materials for the generation of complex target molecules.

1 Introduction

2 Potassium Thioacetate

3 Thiazolidine-2,4-dione

4 Rhodanines

5 Sodium Sulfide

6 Thiotetronic Acid

7 Thiadiazoles

8 Thiophene

9 Rongalite

10 Sulfur Dioxide

11 Divinyl Sulfone

12 Sulfur Heterocycles Based on Boronic Acids

13 Miscellaneous

14 Summary

Abstract Image

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设计含硫支架的合成策略
硫杂环在有机合成中的利用因其广泛的应用而备受关注。本综述展示了嵌入氨基酸衍生物、多环、螺环、环烷和其他复杂支架的各种硫杂环的合成。所报道的方法不仅限于化合物合成,还强调了使用不同的硫试剂来构建硫杂环。本综述还讨论了各种含硫起始材料在生成复杂目标分子方面的用途。1 引言 2 硫代乙酸钾 3 噻唑烷-2,4-二酮 4 罗丹宁类 5 硫化钠 6 硫代四氢呋喃 7 噻二唑 8 噻吩 9 荣格列特 10 二氧化硫 11 二乙烯基砜 12 基于硼酸的硫杂环 13 杂项 14 总结
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