Comparative Study of Crossover Mathematical Model of Breast Cancer Based on Ψ-Caputo Derivative and Mittag-Leffler Laws: Numerical Treatments

Abstract

Two novel crossover models for breast cancer that incorporate Ψ-Caputo fractal variable-order fractional derivatives, fractal fractional-order derivatives, and variable-order fractional stochastic derivatives driven by variable-order fractional Brownian motion and the crossover model for breast cancer that incorporates Atangana–Baleanu Caputo fractal variable-order fractional derivatives, fractal fractional-order derivatives, and variable-order fractional stochastic derivatives driven by variable-order fractional Brownian motion are presented here, where we used a simple nonstandard kernel function Ψ(t) in the first model and a non-singular kernel in the second model. Moreover, we evaluated our models using actual statistics from Saudi Arabia. To ensure consistency with the physical model problem, the symmetry parameter ζ is introduced. We can obtain the fractal variable-order fractional Caputo and Caputo–Katugampola derivatives as special cases from the proposed Ψ-Caputo derivative. The crossover dynamics models define three alternative models: fractal variable-order fractional model, fractal fractional-order model, and variable-order fractional stochastic model over three-time intervals. The stability of the proposed model is analyzed. The Ψ-nonstandard finite-difference method is designed to solve fractal variable-order fractional and fractal fractional models, and the Toufik–Atangana method is used to solve the second crossover model with the non-singular kernel. Also, the nonstandard modified Euler–Maruyama method is used to study the variable-order fractional stochastic model. Numerous numerical tests and comparisons with real data were conducted to validate the methods’ efficacy and support the theoretical conclusions.