Synthesis of Novel 6 H-Furo[3,2-e]Indole Derivatives via One-Pot Three Component Reactions

IF 2 3区 化学 Q2 CHEMISTRY, ORGANIC Journal of Heterocyclic Chemistry Pub Date : 2024-08-28 DOI:10.1002/jhet.4883
Dan-Dan Wan, Shuang-Ling Wu, Jia-Yan Liu, Dong-Sheng Chen
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Abstract

A one-pot, three-component reaction of ethyl 5-aminobenzofuran-2-carboxylate, arylglyoxals and cyclic 1,3-dicarbonyl compounds in the presence of acetic acid as an organocatalyst in ethanol medium under reflux conditions provided a series of new 6H-furo[3,2-e]indole derivatives in good yields.

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通过一锅三组份反应合成新型 6H-呋喃并[3,2-e]吲哚衍生物
在乙酸作为有机催化剂的存在下,在乙醇介质中,在回流条件下,5-氨基苯并呋喃-2-甲酸乙酯、芳基乙醛和环 1,3-二羰基化合物发生了单锅三组分反应,以良好的收率获得了一系列新的 6H-呋喃并[3,2-e]吲哚衍生物。
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来源期刊
Journal of Heterocyclic Chemistry
Journal of Heterocyclic Chemistry 化学-有机化学
CiteScore
5.20
自引率
4.20%
发文量
177
审稿时长
3.9 months
期刊介绍: The Journal of Heterocyclic Chemistry is interested in publishing research on all aspects of heterocyclic chemistry, especially development and application of efficient synthetic methodologies and strategies for the synthesis of various heterocyclic compounds. In addition, Journal of Heterocyclic Chemistry promotes research in other areas that contribute to heterocyclic synthesis/application, such as synthesis design, reaction techniques, flow chemistry and continuous processing, multiphase catalysis, green chemistry, catalyst immobilization and recycling.
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